Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial

Wang Qi; Yang Ji-xiang; Li Guo-xin; Xia Zhong-yuan; Wang Bin; Li Xian-chu; Hu Hai-xiang; Bi Huan-zhou; Xu Fu-song; He Ying; Lin Tian-dong

doi:10.1007/BF02836376

Your Location：

Home >

Browse articles >

Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial

OriginalPaper | Updated：2021-08-27

- Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial
- Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial
- 中国结合医学杂志（英文版） 2004年10卷第2期页码：96-101
- Affiliations：
  
  1. Beijing University of Chinese Medicine,Beijing
  2. The Affiliated Hospital of Liaoning TCM College,Shenyang
  3. Japan Friendship Hospital,Beijing,China
  4. Beijing TCM Hospital,Beijing
  5. The General Hospital of Airforce,Beijing
  6. The Second Affiliated Hospital of Heilongjiang University of TCM,Harbin
  7. Jiangsu Provincial TCM Hospital,Nanjing
  8. Hainan Provincial TCM Hospital,Haikou
- Author bio：
- Funds：
- DOI：10.1007/BF02836376
  中图分类号：
- 纸质出版日期：2004，
Scan for full text
Qi, W., Ji-xiang, Y., Guo-xin, L. et al. Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial., Chin. J. Integr. Med. 10, 96–101 (2004). https://doi.org/10.1007/BF02836376

Wang Qi, Yang Ji-xiang, Li Guo-xin, et al. Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2004,10(2):96-101.
Qi, W., Ji-xiang, Y., Guo-xin, L. et al. Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial., Chin. J. Integr. Med. 10, 96–101 (2004). https://doi.org/10.1007/BF02836376 DOI：

Wang Qi, Yang Ji-xiang, Li Guo-xin, et al. Treatment of patients with erectile dysfunction by Shugan Yiyang Capsule: A multi-centered randomized controlled trial[J]. Chinese Journal of Integrative Medicine, 2004,10(2):96-101. DOI： 10.1007/BF02836376.

摘要

Objective: To evaluate the efficacy and safety of Shugan Yiyang Capsule (SGYY) in treating psychogenic and mild arteriogenic erectile dysfunction (ED) of Gan stagnation and Shen deficiency Syndrome type with or without blood stasis.Methods: A multi-centered

randomized

double-blinded

placebo-controlled trial in 304 patients was conducted by dividing them into 3 groups

who received respectively SGYY (n = 102)

placebo (n = 101) and Suoyang Bushen capsule (SYBS

n = 101)

1. Og taken three times a day for 4 weeks. Besides

205 patients were arranged in an open-label study and treated with SGYY l.0 g taken three times a day for 4 weeks. The total effective rate

total remarkably effective rate

erection recovery rate tested by penis hardness test ring

time taken for improving erection among groups

as well as therapeutic effect between psychogenic ED group and mild arteriogenic ED group were compared. Adverse reactions related to SGYY were recorded. And a 3-month follow-up study was conducted on 105 cured patients.Results: The trial was completed in 500 patients. The total effective rate and total remarkably effective rate in the SGYY treated double-blinded group were 88.0% and 64.0% respectively

and those in the open-label group 90.5% and 65.0%

respectively

all significantly higher than those in the placebo (21.0%

6.0%) and SYBS groups (60.0%

29.0%)

P<0.01. At the same time

the erection recovery rate and improving time in SGYY group were significantly better than those in other groups (P<0.01). No adverse reactions related to SGYY were found. The successful rate of potency to have intercourse within 3 months was over 80% (100 patients out of the 105 cured patients).Conclusion: SGYY was an effective and safe treatment for patients with psychogenic and mild arteriogenic ED of Gan stagnation and Shen deficiency Syndrome type with or without blood stasis

especially for psychogenic ED patients.

Abstract

randomized

double-blinded

placebo-controlled trial in 304 patients was conducted by dividing them into 3 groups

who received respectively SGYY (n = 102)

placebo (n = 101) and Suoyang Bushen capsule (SYBS

n = 101)

1. Og taken three times a day for 4 weeks. Besides

205 patients were arranged in an open-label study and treated with SGYY l.0 g taken three times a day for 4 weeks. The total effective rate

total remarkably effective rate

erection recovery rate tested by penis hardness test ring

time taken for improving erection among groups

and those in the open-label group 90.5% and 65.0%

respectively

all significantly higher than those in the placebo (21.0%

6.0%) and SYBS groups (60.0%

29.0%)

P<0.01. At the same time

especially for psychogenic ED patients.

关键词

Shugan Yiyang Capsuleerectile dysfunctionrandomized controlled trial

Keywords

Shugan Yiyang Capsuleerectile dysfunctionrandomized controlled trial

references

Benet AE, Melman A. The epidemiology of erectile dysfunction. Urol Clin North Am 1995; 22: 699–709.

Wang Q, Hong DH. On the theory “Impotence could be treated by regulating Gan”. Tianjin Tradit Chin Med 1985; 2(5): 15–16.

Wang Q, Wu WP. The clinical report of Longhuan capsule in treating erectile dysfunction in Rhesus monkey. In Kang LS, Cui M, editors. Traditional Sexual Medicine in China. 1st Edition. Beijing: Science and Technology Press of Chinese Medicine, 1994: 163–167.

National Institute of Health Consensus Development Panel on Impotence. JAMA 1993; 270: 83–90.

Ministry of Health, P. R. China. Guidance on Principle of Clinical Research of New Chinese Drugs (1st Edition). 1993: 126

Guo YL, Zhu JC, Pan TM, et al. Clinical study of orally taken sildenafil in treating erectile dysfunction, its efficacy and safety. Chin J Urinary Surg 2001; 22(7): 389–394.

FULL TEXT LINK

More>

浏览量

401

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Endorsement of CONSORT by Chinese medical journals: A survey of “instruction to authors”

A randomized controlled trial of adjunctive Bunchang Naoxintong Capsule (步长脑心通胶囊) versus maintenance dose clopidogrel in patients with CYP2C19*2 polymorphism

Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials

Efficacy of Gastrosis No.1 compound on functional dyspepsia of spleen and stomach deficiency-cold syndrome: A multi-center, double-blind, placebo-controlled clinical trial

Syndrome pattern and its application in parallel randomized controlled trials