Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome

Liu Bao-yan; Hu Jing-qing; Xie Yan-ming; Weng Wei-liang; Wang Rong-bing; Zhang Yan-ping; Li Xiu-hui; Zhang Ke; Ren Ai-ming; Li Jun; Wang Bao-guo; Tang Xu-dong; Wang Wei-dong; Ni Qing; Zhang Jin-ping; Wu Hong-jin; Zhou Wei; Geng Zhi; He Yang-bo; Liang Zhi-wei; He Li-yun; Gao Fan-zhu; Peng Jin

doi:10.1007/BF02836381

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Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome

OriginalPaper | Updated：2021-08-27

- Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome
- Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome
- 中国结合医学杂志（英文版） 2004年10卷第2期页码：117-122
- Affiliations：
  
  1. Clinical Evaluation Center, China Academy of TCM,China
  2. Xiyuan Hospital, China Academy of TCM,China
  3. Beijing Municipal Ditan Hospital,China
  4. Beijing Municipal You’an Hospital,China
  5. Beijing Friendship Hospital,China
  6. Hospital,PLA,China,302
  7. Beijing Tiantan Hospital,China
  8. Guang anmen Hospital, China Academy of TCM,China
  9. Beijing Municipal Chest Hospital,China
  10. Beijing Municipal Hospital of Integrative Traditional Chinese and Western Medicine,China
  11. Wangjing Hospital, China Academy of TCM,China
  12. Peking University,China
  13. Guangdong Provincial Hospital of TCM,China
- Author bio：
- Funds：
  
  This item is one of the items of State 863 Plan (No. 2003AA208101);a special subject of clinical study of State administration of TCM;and an important item of Beijing Scientific-Technology Plan(No. H020920010031)
- DOI：10.1007/BF02836381
  中图分类号：
- 纸质出版日期：2004，
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Bao-yan, L., Jing-qing, H., Yan-ming, X. et al. Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome., Chin. J. Integr. Med. 10, 117–122 (2004). https://doi.org/10.1007/BF02836381

Liu Bao-yan, Hu Jing-qing, Xie Yan-ming, et al. Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome[J]. Chinese Journal of Integrative Medicine, 2004,10(2):117-122.
Bao-yan, L., Jing-qing, H., Yan-ming, X. et al. Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome., Chin. J. Integr. Med. 10, 117–122 (2004). https://doi.org/10.1007/BF02836381 DOI：

Liu Bao-yan, Hu Jing-qing, Xie Yan-ming, et al. Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome[J]. Chinese Journal of Integrative Medicine, 2004,10(2):117-122. DOI： 10.1007/BF02836381.

摘要

Objective: To evaluate the effects of treatment of integrative Chinese and Western medicine (ICWM) on arterial oxygen saturation (SaO2) in patients with severe acute respiratory syndrome (SARS).Methods:The non-randomized

controlled trial was conducted on 447 SARS patients treated synchronously with western conventional treatment (WM group

n = 171) alone and ICWM (ICWM group

n = 276). The changes of the cases with normal level (≥95%) or abnormal level (<95%) SaO2 were observed dynamically.Results: In the 3rd-14th day of the therapeutic course

the percentage of patients with normal SaO2 in the ICWM group was higher than that in the WM group (OR = 0. 5178

P = 0.0038)

and this tendency was more evident in patients of the severe type (OR = 0.18

P = 0.0001). However

the statistical significance of difference was only shown in patients for whom the ICWM treatment started in the early period after the onset (<-7 days after it

OR = 0.3803

P = 0.006)

but not shown in those who received ICWM treatment later in the mid-late period of SARS (P>0.05).Conclusion: ICWM treatment

particularly when it is used for intervention in the early stage

is beneficial for maintaining normal SaO2 in SARS patients.

Abstract

controlled trial was conducted on 447 SARS patients treated synchronously with western conventional treatment (WM group

n = 171) alone and ICWM (ICWM group

n = 276). The changes of the cases with normal level (≥95%) or abnormal level (<95%) SaO2 were observed dynamically.Results: In the 3rd-14th day of the therapeutic course

the percentage of patients with normal SaO2 in the ICWM group was higher than that in the WM group (OR = 0. 5178

P = 0.0038)

and this tendency was more evident in patients of the severe type (OR = 0.18

P = 0.0001). However

the statistical significance of difference was only shown in patients for whom the ICWM treatment started in the early period after the onset (<-7 days after it

OR = 0.3803

P = 0.006)

but not shown in those who received ICWM treatment later in the mid-late period of SARS (P>0.05).Conclusion: ICWM treatment

particularly when it is used for intervention in the early stage

is beneficial for maintaining normal SaO2 in SARS patients.

关键词

Severe Acute Respiratory Syndromearterial oxygen saturationintegrative Chinese and western medicine

Keywords

Severe Acute Respiratory Syndromearterial oxygen saturationintegrative Chinese and western medicine

references

Ministry of Health, People’s Republic of China. The clinical diagnostic criteria of SARS 2003; May, 3.

Ministry of Health, People’s Republic of China. The recommended treatment regimen of SARS. 2003; May, 3.

Ministry of Health, People’s Republic of China. The discharging referential criteria of SARS patients 2003; May, 3.

Nicholls JM, Poon LM, Lee KC, et al. Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003; 361: 773–1778.

Oba Y. The use of corticosteroids in SARS. N Engl J Med 2003; 348: 2034–2035.

Liu ZY, Li TS, Wang Z, et al. Clinical characteristics and treatment summarization of 106 SARS patients. Chin J Int Med 2003; 42(6):373–377.

Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus associated SARS pneumonia: a prospective study. Lancet 2003; 361: 1767–1772.

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So LK, Lau AC, Yam LY, et al. Development of a standard treatment protocol for SARS. Lancet 2003; 361: 1615–1617.

Lin L, Han Y, Yang ZM, et al. Clinical observation on 103 SARS patients with integrative Chinese and western medicine. Chin J Integr Tradit West Med 2003; 23 (6): 409–413.

Li XH, Zhang K, Hu JH, et al. Clinical observation of efficacy ofintegrative Chinese and western medicinein treating SARS. Chin J Integr Tradit West Med 2003; 23 (7): 489–491.

Wang RB, Liu AM, Jiang YB, et al Preliminary analysis on efficacy of integrative Chinese and western medicine in treating SARS. Chin J Integr Tradit Wes Med 2003; 23(7): 492–493.

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