Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models

He Lan; Mao Teng-min

doi:10.1007/BF02836415

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Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models

OriginalPaper | Updated：2021-08-27

- Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models
- Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models
- 中国结合医学杂志（英文版） 2004年10卷第3期页码：226-229
- Affiliations：
  
  The Third Hospital and Basic Medicine Department, Beijing University,Beijing,China
- Author bio：
- Funds：
  
  The project is supported by National Natural Science Foundation (No. 39270814)
- DOI：10.1007/BF02836415
  中图分类号：
- 纸质出版日期：2004，
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Lan, H., Teng-min, M. Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models., Chin. J. Integr. Med. 10, 226–229 (2004). https://doi.org/10.1007/BF02836415

He Lan, Mao Teng-min. Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models[J]. Chinese Journal of Integrative Medicine, 2004,10(3):226-229.
Lan, H., Teng-min, M. Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models., Chin. J. Integr. Med. 10, 226–229 (2004). https://doi.org/10.1007/BF02836415 DOI：

He Lan, Mao Teng-min. Experimental study on observation of hemorheologic parameters of hydrocortisone caused Shen-Yang deficiency in rat models[J]. Chinese Journal of Integrative Medicine, 2004,10(3):226-229. DOI： 10.1007/BF02836415.

摘要

Objective: To explore the relationship between Shen deficiency and blood stasis.Methods: Using consecutive intramuscular injection of hydrocortisone to build Shen-yang deficiency model rats

and detect their hemorheological and biochemical parameters.Results: Comparison between the model group and control group showed that the in vitro thrombus significantly lengthened in the model group (P<0.05)

the dry weight increased (P<0.01)

hematocrit and whole blood viscosity under high sheared change lowered (P<0.05)

blood glucose elevated (P<0.01)

and RBC infiltration index

aggregation index increased (P close to 0.05).Conclusion: Under the condition of Shen-yang deficiency

although blood does not show such properties of blood stasis as being “viscous

concentrated

coagulated and aggregated”

partial change of hemorheology occurs

and it is liable to form thrombus

which proves that the Shen deficiency status is accompanied with the tendency of blood stasis.

Abstract

Objective: To explore the relationship between Shen deficiency and blood stasis.Methods: Using consecutive intramuscular injection of hydrocortisone to build Shen-yang deficiency model rats

the dry weight increased (P<0.01)

hematocrit and whole blood viscosity under high sheared change lowered (P<0.05)

blood glucose elevated (P<0.01)

and RBC infiltration index

aggregation index increased (P close to 0.05).Conclusion: Under the condition of Shen-yang deficiency

although blood does not show such properties of blood stasis as being “viscous

concentrated

coagulated and aggregated”

partial change of hemorheology occurs

and it is liable to form thrombus

which proves that the Shen deficiency status is accompanied with the tendency of blood stasis.

关键词

HydrocortisoneShen deficiencyhemorheology

Keywords

HydrocortisoneShen deficiencyhemorheology

references

Mao TM, Ma ZZ, Li SC, et al. Exploration of blood stasis pathologic model (2). J Beijing Med Univ 1991; 23 (2): 100–102.

Kuang AK, Wu Y, Ding T, et al. Effect of some yang assisting herbs on large dosage corticosterone induced phenomena of exhaustion. Chin J Int Med 1963; 11 (2): 113–116.

Chen MD, Kuang AK, Chen JL, et al. Study on yang assisting herbs on cortisone rat model transmitters effect of blood cerebral monoamines. Chin J Integr Tradit West Med 1990;10(5): 292–294.

Feng RH, Liu HZ, Gao S, et al. The change of Pi deficiency and Shen deficiency mice model change of RBC fluidity. Acad J Guangzhou Univ TCM 2003; 20(1): 21–24.

Liang MLD, Lu LH, Zhang XM, et al. Effect of age increasing to blood stasis syndrome and plasma thromboxane B2 and 6-keto-thromboxane F1α level. Chin J Integr Tradit West Med 1995; 15(11): 652–654.

Fu RJ, chief editor. Foster life and live prolonging. Beijing: Chemical Engineering Press, 1995: 36–37.

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