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Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property
Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property
- 中国结合医学杂志（英文版） 2005年11卷第2期 页码：132-135
- Affiliations：
1. Institute of Space Medico-Engineering,Beijing
2. Institute of Medicinal Plant Development, China Academy of Medical Science,China
- Author bio：
- Funds：Supported by the National Natural Science Foundation of China (No. 39770899)
DOI：10.1007/BF02836470
中图分类号：纸质出版日期：2005，
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Hong-zhi, S., Nan-nan, G., Yong-zhi, L. et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property., Chin. J. Integr. Med. 11, 132–135 (2005). https://doi.org/10.1007/BF02836470
Shi Hong-zhi, Gao Nan-nan, Li Yong-zhi, et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property[J]. Chinese Journal of Integrative Medicine, 2005,11(2):132-135.
Hong-zhi, S., Nan-nan, G., Yong-zhi, L. et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property., Chin. J. Integr. Med. 11, 132–135 (2005). https://doi.org/10.1007/BF02836470 DOI：
Shi Hong-zhi, Gao Nan-nan, Li Yong-zhi, et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property[J]. Chinese Journal of Integrative Medicine, 2005,11(2):132-135. DOI： 10.1007/BF02836470.
摘要
Objective: To study the effects of L. F04
the active fraction ofLycopus lucidus
on erythrocytes rheological property so as to investigate its mechanism in promoting blood circulation and removing blood stasis.Method: The effects of L. F04 (used for treatment for 10 days in different dosages) on deformability
aggregation and membrane liquidity of erythrocytes (MLE) as well as whole blood apparent viscosity (ηb) were examined on the basis of rat model of blood-stasis syndrome induced by venous injection of high molecular weight dextran.Result: As compared with the normal control group
the model group’s RBC deformability and MLE were lower
and the aggregation of erythrocytes and ηb were higher. Compared with the model group
both L. F04 0. 612g/kg and 0.306g/kg showed significant effect in improving deformability and inhibiting aggregation of red blood cells (RBC) and reducing blood viscosity. The trend of improving MLE was also shown.Conclusion: L. F04 could significantly improve the abnormal rheological property of erythrocytes.
Abstract
Objective: To study the effects of L. F04
the active fraction ofLycopus lucidus
on erythrocytes rheological property so as to investigate its mechanism in promoting blood circulation and removing blood stasis.Method: The effects of L. F04 (used for treatment for 10 days in different dosages) on deformability
aggregation and membrane liquidity of erythrocytes (MLE) as well as whole blood apparent viscosity (ηb) were examined on the basis of rat model of blood-stasis syndrome induced by venous injection of high molecular weight dextran.Result: As compared with the normal control group
the model group’s RBC deformability and MLE were lower
and the aggregation of erythrocytes and ηb were higher. Compared with the model group
both L. F04 0. 612g/kg and 0.306g/kg showed significant effect in improving deformability and inhibiting aggregation of red blood cells (RBC) and reducing blood viscosity. The trend of improving MLE was also shown.Conclusion: L. F04 could significantly improve the abnormal rheological property of erythrocytes.
关键词
Lycopus lucidusblood-stasisdeformability of erythrocytesaggregation of erythrocytesmembrane liquidity of erythrocyteswhole blood apparent viscosityL. F04
Keywords
Lycopus lucidusblood-stasisdeformability of erythrocytesaggregation of erythrocytesmembrane liquidity of erythrocyteswhole blood apparent viscosityL. F04
references
Liu XM, Gao NN, Yu SR, et al. Improving effects of Shiny bugleweed (Lycopus lucidus) on blood stasis syndrome of rabbit induced by simulating weightlessness. Chin Tradit Herbal Drugs 1991; 22(11): 501–503.
Zhang YJ, Rang B, Zhang WD, et al. Effects of herba lycopi on hemorheology and bulbar conjunctival microcirculation in rabbits. Chin J Microcircul 1996; 6(2): 31–32.
Hu HJ, Qi GR, Chen YX, et al. Anticoagulation of herb Lycopus lucydus decoction. Acta Pharmacol Sinica 1995; 11(6): 28–31.
Zhang YJ, Kang B, Geng XF, et al. Study on effect of herba Lycopy in depressing blood-lipid. J Wei Fang Med Coll 1993; 15(1): 16–17, 33.
Gao NN, Tian Z, Li LL, et al. Pharmacological studies on the blood-activating and stasis-resolving effects of Shiny bugleweed (Lycopus lucidus) I: Effects of four extract fractions of Shing Bugleweed on the hemorrheology of rat. Chin Tradit Herbal Drugs 1996; 27 (6): 352–355.
Tian N. Methodology of microcirculation research. Beijing: Press of Atomic Energy, 1993: 292–293.
Weng WL, Liao FL, Wu YP. Methodology and Application of hemorrheology. Beijing: Press of Science, 1989: 96–99.
Shen XY, Xiang QL, Meng JR. Effects of two Chinese herbs on rabbit’s ear microcirculation under simulated weightlessness. Space Medicine & Medico Engineering 1993; 6(1): 1–5.
Shen XY, Xiang QL, Meng JR, et al. Effects of Chinese herbs in improving the blood circulation of rabbits under simulated weightlessness. Space Medicine & Medico Engineering 1997; 10(6): 396–400.
Dong Q, Shen XY, Chen JH, et al. Effects of simulated weightlessness on erythrocyte deformability in rat. Space Medicine & Medico Engineering 1997; 10 (4): 240–244.
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