Ping, L., Qiu-dong, L., Rong, L. et al. Effect of traditional Chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy., Chin. J. Integr. Med. 12, 175–179 (2006). https://doi.org/10.1007/BF02836517
Lu Ping, Liang Qiu-dong, Li Rong, et al. Effect of traditional Chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy[J]. Chinese Journal of Integrative Medicine, 2006,12(3):175-179.
Ping, L., Qiu-dong, L., Rong, L. et al. Effect of traditional Chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy., Chin. J. Integr. Med. 12, 175–179 (2006). https://doi.org/10.1007/BF02836517DOI:
Lu Ping, Liang Qiu-dong, Li Rong, et al. Effect of traditional Chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy[J]. Chinese Journal of Integrative Medicine, 2006,12(3):175-179. DOI: 10.1007/BF02836517.
Effect of traditional Chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy
摘要
Objective: To explore the effect and possible mechanism of traditional Chinese medicine (TCM) on survival and quality of life (QOL) in patients with esophageal carcinoma after esophagectomy.Methods: Adopting prospective controlled method of study
the authors had 128 post-esophagectomy patients
hospitalized from February 2001 to February 2002
randomly divided into 3 groups: the TCM group
treated with TCM drugs alone; the chemotherapy group
with chemotherapy alone applied; and the synthetic group
treated with chemotherapy combined with Chinese medicine. Their survival rate and QOL were compared.Results: In the TCM group
the chemotherapy group and the synthetic group
the respective 3-year relapse and remote metastasis rate were 71.4%
76.7%
53.4%
respectively (x2 = 6.53
P < 0.05); the 1-year survival rate 42.9%
46.5%
72.1 %; 2-year survival rate 28.6%
27.9%
55.8%
and 3-year survival rate 26. 2%
23. 1%
37. 2%
respectively. And the QOL improving rate was 69. 0%
37. 2%
58.1%
respectively
all showing significant difference among them (x2 = 6. 10
allP < 0.05). Moreover
immune function was increased in the TCM and the synthetic groups.Conclusion: Integrative Chinese and Western medicinal treatment was the beneficial choice for post-operational patients with esophageal carcinoma. However
long time use of simple Chinese medicine was also advisable
especially for those in poverty.
Abstract
Objective: To explore the effect and possible mechanism of traditional Chinese medicine (TCM) on survival and quality of life (QOL) in patients with esophageal carcinoma after esophagectomy.Methods: Adopting prospective controlled method of study
the authors had 128 post-esophagectomy patients
hospitalized from February 2001 to February 2002
randomly divided into 3 groups: the TCM group
treated with TCM drugs alone; the chemotherapy group
with chemotherapy alone applied; and the synthetic group
treated with chemotherapy combined with Chinese medicine. Their survival rate and QOL were compared.Results: In the TCM group
the chemotherapy group and the synthetic group
the respective 3-year relapse and remote metastasis rate were 71.4%
76.7%
53.4%
respectively (x2 = 6.53
P < 0.05); the 1-year survival rate 42.9%
46.5%
72.1 %; 2-year survival rate 28.6%
27.9%
55.8%
and 3-year survival rate 26. 2%
23. 1%
37. 2%
respectively. And the QOL improving rate was 69. 0%
37. 2%
58.1%
respectively
all showing significant difference among them (x2 = 6. 10
allP < 0.05). Moreover
immune function was increased in the TCM and the synthetic groups.Conclusion: Integrative Chinese and Western medicinal treatment was the beneficial choice for post-operational patients with esophageal carcinoma. However
long time use of simple Chinese medicine was also advisable
especially for those in poverty.
关键词
post-esophagectomytraditional Chinese drug therapyquality of lifeSurvival Rate
Keywords
post-esophagectomytraditional Chinese drug therapyquality of lifeSurvival Rate
references
Ho YP, To KK, Au-Yeung SC, et al. Potential new antitumor agents from an innovative combination of demethylcantharidin, a modified traditional Chinese medicine, with a platinum moiety. J Med Chem 2001;44 (13): 2065–2068.
Jin CJ, Li L, Cui Q, et al. Clinical observation of Chinese medicine in combined with Western medicine after the operation of esophageal carcinoma. Tumor 2003;23 (5): 429–431.
Zhou JC, editor. Practice of medical oncology. 2nd ed. Beijing: People’ s Medical Publishing House, 2003: 572–588.
Ye JH, Li YL. Clinical progress of the combined Chinese and Western medicine on esophageal carcinoma. Beijing J Tradit Chin Med 1998;1(3): 41–43.
Yu GQ, Sun Y. Clinical practice of Chinese medicine in multidisciplinary treatment of cancer. Beijing: People’s Medical Publishing House, 2001: 478.
Zhang RG. Issues today in esophageal carcinoma. J Post-graduates Med 2005;6(8): 13–15, 27.
Zhou DH, editor. Clinical oncology in Chinese medicine. Beijing: People’s Medical Publishing House, 2003: 162–164.
Sun GZ, Li J, Wang HZ. Clinical progress of the combined Chinese and Western medicine on esophageal carcinoma. J Med Theory Practice 1997;9(10): 433–434.
Li PW, editor. Clinical oncology in Chinese and Western medicine. Beijing: China Press of Traditional Chinese Medicine, 1996: 690–691.
Zhang KM. Clinical effects of the combined Chinese and Western medicine on post-operation of cardia carcinoma. Shanxi J Tradit Chin Med 1999;15(6): 22.
Wang LS, Lin HY, Chang C J, et al. Effects of en bloc esophagectomy on nutritional and immune status in patients with esophageal carcinoma. J Surg Oncol 1998;67 (2): 90–99.
Ashiro T, Yamamori H, Takagi K, et al. Changes in immune function following surgery for esophageal carcinoma. Nutrition 1999;15(10): 760–766.
Shi H, Gu XC, Zhu L, et al. Effects of large dose thymopeptides on T-cell subpopulations of patients with malignant hematologic diseases under chemotherapy. J Clin Hematol 2000;13(3): 112.
Huang XW, Luo QD. Traditional Chinese medicine therapy of esophageal cancer. Chin J Pract Chin Modern Med 2003;3(16): 1436–1437.
Standardized treatment of chinese medicine decoction for cancer pain patients with opioid-induced constipation: A multi-center prospective randomized controlled study
Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease
Advising on Preferred Reporting Items for patient-reported outcome instrument development: the PRIPROID
Effects of Chinese medicine five-element music on the quality of life for advanced cancer patients: A randomized controlled trial
Chinese medicine improves postoperative quality of life in endometriosis patients: A randomized controlled trial
相关作者
暂无数据
相关机构
Department of Oncology, First Affiliated Hospital of Guangzhou University of Chinese Medicine
Department of Respiratory, Huaihe Hospital of Henan University
Department of Respiratory, Kaifeng Hospital of Traditional Chinese Medicine
Department of Respiratory, the Second People’s Hospital of Jiaozuo City
Department of Acupuncture and Moxibustion, the Third Affiliated Hospital of Henan University of Traditional Chinese Medicine