Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction

Zhang Jin-guo; Gao Dong-sheng; Yang Na; Liu Li-xin; He Hua; Dong Hai-xin; Liu Xue-ling; Chen Ting; Wang Xue-zhong; Liu Ya-jie

doi:10.1007/BF02838559

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Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction

OriginalPaper | Updated：2021-08-27

- Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction
- Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction
- 中国结合医学杂志（英文版） 2003年9卷第2期页码：104-107
- Affiliations：
  
  1. Affiliated Hospital of Jining Medical College,Shandong
  2. Hebei Provincial People’s Hospital,Shijiazhuang
  3. Jining Medical College,Shandong
- Author bio：
- Funds：
- DOI：10.1007/BF02838559
  中图分类号：
- 纸质出版日期：2003，
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Jin-guo, Z., Dong-sheng, G., Na, Y. et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction., Chin. J. Integr. Med. 9, 104–107 (2003). https://doi.org/10.1007/BF02838559

Zhang Jin-guo, Gao Dong-sheng, Yang Na, et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2003,9(2):104-107.
Jin-guo, Z., Dong-sheng, G., Na, Y. et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction., Chin. J. Integr. Med. 9, 104–107 (2003). https://doi.org/10.1007/BF02838559 DOI：

Zhang Jin-guo, Gao Dong-sheng, Yang Na, et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction[J]. Chinese Journal of Integrative Medicine, 2003,9(2):104-107. DOI： 10.1007/BF02838559.

摘要

Objective: To observe the effect of Astragalus Injection (AI) on left ventricular remodeling in aged patients with acute myocardial infarction (AMI).Methods: Patients with AMI were randomly divided into the AI group (46 cases) treated with AI and the control group (46 cases) treated conventionally. Left ventricular end-diastolic volume index (LVEDVI)

left ventricular end-systolic volume index (LVESVI)

anterior endocardial segmental length (ASL) and posterior endocardial segmental length (PSL) were all assessed by echocardiogram after 1 week and 4 weeks treatment. The cardiac systolic and diastolic functions were detected by nuclide gating cardiac blood pool imaging at the 4th week.Results: After four weeks’ treatment

no obvious change of LVEDVI

LVESVI and ASL in the AI group was found

but these indexes increased significantly in the control group

with significant difference shown between the two groups (P<0.05). As compared with the control group

the left ventricular ejection fraction (LVEF)

left ventricular peak ejecting rate (LVPER) and left ventricular peak filling rate (LVPFR) were heightened

the time for peak filling rate (LVTPFR) in the left ventricle was shortened in the AI group.Conclusion: AI is one of the effective drugs in reversing left ventricular remodeling in aged patients with AMI.

Abstract

left ventricular end-systolic volume index (LVESVI)

no obvious change of LVEDVI

LVESVI and ASL in the AI group was found

but these indexes increased significantly in the control group

with significant difference shown between the two groups (P<0.05). As compared with the control group

the left ventricular ejection fraction (LVEF)

left ventricular peak ejecting rate (LVPER) and left ventricular peak filling rate (LVPFR) were heightened

关键词

myocardial infarctionthe agedleft ventricular remodelingAstragalus Injection

Keywords

myocardial infarctionthe agedleft ventricular remodelingAstragalus Injection

references

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HONG Y, XU SZ, ZENG DY, et al. Study of the inhibitory effect of Astragalus Injection on experimental cardiac hypertrophy in rats. Chin Tradi Patient Med 2002; 24(7): 525–529.

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