High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome

Guo Ping-qing; Lin Qiu-cheng; Guo Yin-geng; Shen Zong-guo

doi:10.1007/BF02838562

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High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome

OriginalPaper | Updated：2021-08-27

- High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome
- High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome
- 中国结合医学杂志（英文版） 2003年9卷第2期页码：112-115
- Affiliations：
  
  1. The First Affiliated Hospital of Fujian Medical University,Fuzhou
  2. Fujian TCM College,China
- Author bio：
- Funds：
- DOI：10.1007/BF02838562
  中图分类号：
- 纸质出版日期：2003，
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Ping-qing, G., Qiu-cheng, L., Yin-geng, G. et al. High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome., Chin. J. Integr. Med. 9, 112–115 (2003). https://doi.org/10.1007/BF02838562

Guo Ping-qing, Lin Qiu-cheng, Guo Yin-geng, et al. High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome[J]. Chinese Journal of Integrative Medicine, 2003,9(2):112-115.
Ping-qing, G., Qiu-cheng, L., Yin-geng, G. et al. High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome., Chin. J. Integr. Med. 9, 112–115 (2003). https://doi.org/10.1007/BF02838562 DOI：

Guo Ping-qing, Lin Qiu-cheng, Guo Yin-geng, et al. High density lipoprotein phospholipids as a marker of coronary heart disease of shen-Yang deficiency syndrome[J]. Chinese Journal of Integrative Medicine, 2003,9(2):112-115. DOI： 10.1007/BF02838562.

摘要

Objective: To seek a new biochemical index for diagnosis of coronary heart disease (CHD) of shen-Yang deficiency syndrom (CHD-SYD).Methods: Sixty-one patients with CHD were divided into 3 groups according to their TCM Syndrome type

10 patients in the group without Xin-Qi deficiency (Group A)

25 in the group with Xin-Qi deficiency but without Shen-Yang deficiency (Group B) and 26 in the group both with Xin-Qi deficiency and Shen-Yang deficiency (Group C). Levels of 17-hydroxy-corticosteroid in urine (urinary 17-OHCS) per 24 hrs

and serum level of high density lipoprotein cholesterol (HDL-C) and high density lipoprotein phospholipid (HDL-PL) in them were determined in synchrostep and compared with those in the control group of 23 healthy aged persons

urinary 17-OHCS per 24 hrs was taken as the diagnostic standard to screen a new index for diagnosis of Shen-Yang deficiency Syndrome

and preliminary appraisal to the index was made.Results: Serum HDL-PL in the CHD-SYD patients(Group C) was 616±157 mg/L

which was obviously lower than that in the patients of Group A and B. With low HDL-PL (<650 mg/L) used as the index to diagnose CHD-SYD

the sensitivity was 73%

the specificity 86% and the accuracy 80%.Conclusion: HDL-PL <650 mg/L could be adopted as an index for CHD-SYD diagnosis

which is simple and practical.

Abstract

10 patients in the group without Xin-Qi deficiency (Group A)

urinary 17-OHCS per 24 hrs was taken as the diagnostic standard to screen a new index for diagnosis of Shen-Yang deficiency Syndrome

and preliminary appraisal to the index was made.Results: Serum HDL-PL in the CHD-SYD patients(Group C) was 616±157 mg/L

which was obviously lower than that in the patients of Group A and B. With low HDL-PL (<650 mg/L) used as the index to diagnose CHD-SYD

the sensitivity was 73%

the specificity 86% and the accuracy 80%.Conclusion: HDL-PL <650 mg/L could be adopted as an index for CHD-SYD diagnosis

which is simple and practical.

关键词

coronary heart diseaseShen-Yang deficiency Syndromeurinary 17-hydroxy-corticosteroidserum high density lipoprotein phospholipidsserum high density lipoprotein cholesterol

Keywords

coronary heart diseaseShen-Yang deficiency Syndromeurinary 17-hydroxy-corticosteroidserum high density lipoprotein phospholipidsserum high density lipoprotein cholesterol

references

International Academy and Association of Cardiology, Combined Group of Nomenclature Standarization of WHO. Nomenclature and Diagnostic Standard for Ischemic Heart Disease. Chin J Cardiol 1981; 9(1): 75.

WU RR. Relationship between circadian rhythm change of urinary 17-hydoxycortocoid in patients with coronary heart disease of Yin-deficiency type. CJIM(Chin) 1982; 2 (2): 100.

Special Committee of Cardiovascular Disease, Chinese Association of the Integration of Traditional and Western Medicine. Standard for TCM Syndrome differentiation of coronary heart disease. CJIM(Chin) 1991; 11(5): 257.

Francine M. Variations in the composition of low-and high-density lipoproteins during the acute phase of myocardial infarction. Clin Chem 1988; 34(1): 139–140.

Lan-Hsia S, Duncan R, Schob AH, et al. Serum levels of high density lipoprotein phospholipids correlate inversely with severity of angiographically defined coronary artery disease. Atherosclerosis 2000; 152(2): 469–473.

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