Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release

Yu Chuan-xing; Zhu Ling

doi:10.1007/BF02838614

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Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release

OriginalPaper | Updated：2021-08-27

- Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release
- Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release
- 中国结合医学杂志（英文版） 2003年9卷第4期页码：276-280
- Affiliations：
  
  1. Respiratory Diseases Dept. of Fujian Provincial Second People’s Hospital,Fuzhou
  2. Immunology Dept. of Fujian Medical University,China
- Author bio：
- Funds：
  
  The item is subsidized by Natural Science Fund of Fujian Province (No. C96044)
- DOI：10.1007/BF02838614
  中图分类号：
- 纸质出版日期：2003，
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Chuan-xing, Y., Ling, Z. Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release., Chin. J. Integr. Med. 9, 276–280 (2003). https://doi.org/10.1007/BF02838614

Yu Chuan-xing, Zhu Ling. Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release[J]. Chinese Journal of Integrative Medicine, 2003,9(4):276-280.
Chuan-xing, Y., Ling, Z. Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release., Chin. J. Integr. Med. 9, 276–280 (2003). https://doi.org/10.1007/BF02838614 DOI：

Yu Chuan-xing, Zhu Ling. Experimental researches on inhibitory effect of Huoxiang Zhengqi liquid on histamine release[J]. Chinese Journal of Integrative Medicine, 2003,9(4):276-280. DOI： 10.1007/BF02838614.

摘要

Objective: To observe the blocking effect of Huoxiang Zhengqi liquid HXZQL) on histamine release of basophils.Methods: The study was conducted using HXZQL to neutralize and block IgE and antagonize the effect of IL-3 induced enhancing histamine release of bosaphils. Concentration and percentage of histamine release of bosaphils were tested by the basophil histamine release test.Results: The HXZQL drug-serum had obvious inhibitive effect on degranulation of bosaphils induced by IgE antigen-antibody complex (P < 0. 05) and can successfully weaken the histamine release of basophils stimulated by IL-3. When compared with those in the untreated group

it showedP < 0. 01.Conclusion: HXZQL drug-serum may neutralize and block IgE and has inhibitive effects on degranulation of cells when resensitized by antigens. It can also block allergic response type I by antagonizing the effect of IL-3 induced enhancing histamine release.

Abstract

关键词

Huoxiang Zhengqi liquidbasophilshistamine releaseimmunoglobulin Einterleukin 3

Keywords

Huoxiang Zhengqi liquidbasophilshistamine releaseimmunoglobulin Einterleukin 3

references

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