Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder
Back to article page
OriginalPaper|Updated:2021-08-27
|
Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder
Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder
中国结合医学杂志(英文版)2006年12卷第2期 页码:122-125
Affiliations:
Department of Integrated Chinese and Western Medicine, Xiehe Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology,Wuhan
Author bio:
Funds:
Supported by the Fund of Hubei Administration of Health (No. 3-98)
Sheng-lan, Y., Dao-ben, L. Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder., Chin. J. Integr. Med. 12, 122–125 (2006). https://doi.org/10.1007/BF02857358
Yang Sheng-lan, Li Dao-ben. Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder[J]. Chinese Journal of Integrative Medicine, 2006,12(2):122-125.
Sheng-lan, Y., Dao-ben, L. Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder., Chin. J. Integr. Med. 12, 122–125 (2006). https://doi.org/10.1007/BF02857358DOI:
Yang Sheng-lan, Li Dao-ben. Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder[J]. Chinese Journal of Integrative Medicine, 2006,12(2):122-125. DOI: 10.1007/BF02857358.
Clinical study on therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder
摘要
Objective: To explore the clinical effect of therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder (GEFD).Methods: Retrospective analysis was carried out on 96 critical patients. They were 48 patients in the treated group treated with Dachengqi Decoction and 48 patients in the control group treated with Western medicine for promoting gastric dynamic force. The recovery rate
recovery time of gastro-enteric function
incidence rate and fatality rate of multiple organ dysfunction syndrome (MODS)
as well as the level of plasma endotoxin (ET) before and after treatment between the two groups were compared.Results: Comparison between the two groups in gastro-enteric function recovery rate (81.3% vs 45.8%)
functional disorder sustaining time in patients who got recovered (1.2±0.3 days vs 4.0±1.1 days)
incidence rate (29. 17% vs 52.08%) and fatality rate (28.57% vs 56.00%) of MODS all showed significant difference (P< 0.05 orP< 0.01). The plasma level of ET after treatment in the treated group was significantly lower than that in the control group (P< 0. 05).Conclusion: Therapy of clearing hallow viscera has a good effect in treating critical patients with gastro-enteric function disorder
and could reduce the incidence and fatality of MODS.
Abstract
Objective: To explore the clinical effect of therapy of clearing hallow viscera in treating critical patients with gastro-enteric function disorder (GEFD).Methods: Retrospective analysis was carried out on 96 critical patients. They were 48 patients in the treated group treated with Dachengqi Decoction and 48 patients in the control group treated with Western medicine for promoting gastric dynamic force. The recovery rate
recovery time of gastro-enteric function
incidence rate and fatality rate of multiple organ dysfunction syndrome (MODS)
as well as the level of plasma endotoxin (ET) before and after treatment between the two groups were compared.Results: Comparison between the two groups in gastro-enteric function recovery rate (81.3% vs 45.8%)
functional disorder sustaining time in patients who got recovered (1.2±0.3 days vs 4.0±1.1 days)
incidence rate (29. 17% vs 52.08%) and fatality rate (28.57% vs 56.00%) of MODS all showed significant difference (P< 0.05 orP< 0.01). The plasma level of ET after treatment in the treated group was significantly lower than that in the control group (P< 0. 05).Conclusion: Therapy of clearing hallow viscera has a good effect in treating critical patients with gastro-enteric function disorder
and could reduce the incidence and fatality of MODS.
关键词
therapy of clearing hallow visceraDachengqi decoctiongastro-enteric function disorderMultiple Organ Dysfunction Syndrome
Keywords
therapy of clearing hallow visceraDachengqi decoctiongastro-enteric function disorderMultiple Organ Dysfunction Syndrome
references
Yang SL, Wang P, Li DB. Expermental study on the mechanism of protective effect of clearing the hollow fuorgans on the lung’s damage caused by partly ligating the large intestine. Chin J Integr Tradit West Med Dig 2003; 11(3): 154–156.
Li WF, Chen J, Yang XY, et al. Clinical observation on effect of rhubarb in treating patients with acute respiratory distress. Chin J Crit Care Med 2003; 23(2): 102.
Qin HB, Zhou SX. Modern therapy of multiple organ dysfunction syndrome. Beijing: People’s Military Medical Press, 2001: 20–29.
Hassoun HT, Kone BC, Mercer DW, et al. Postinjury multiple organ failure: the role of the gut. Shock 2001; 15: 1.
Moore FA. The role of the gastrointestinal tract in postinjury multiple organ failure. Am J Surg 1999; 178: 449–453.
Doig CJ, Sutherland LR, Sandham JD, et al. Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients. Am J Respir Crit Care Med 1998; 158: 444–451.
Chen DC, Jing BW, Yang XY, et al. Exploration on the mechanism of rhubarb in protecting intestinal membranous barrier. Chin Crit Care Med 1996; 8 (8): 449–451.
Wang KF, Lu FE, Xu LJ, et al. Comparative studies of therapeutic characteristics of three Chinese herbal preparations against febrile diseases on treating endotoxemic rabbits. J Microcirculation 2002; 12(4): 33–35.
Liu F, Gao SJ, Hu HG, et al. Clinical study on treatment of shock induced gastro-enteric function disorder by rhubarb. Chin J Crit Care Med 2003; 23(1): 38–39.
Thijis LG, Hack CE. Time course of cytokine levels in sepsis. Intesive Care Med 1995; 21: 258–263.
Morphological changes in network of enteric nerve-interstitial cells of Cajal-smooth muscle cells in rats with multiple organ dysfunction syndrome and therapeutic effects of Dachengqi decoction (大承气汤)
Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction (大承气汤) in rats
Clinical observation on the effect of dexamethasone and chinese herbal decoction for purgation in severe acute pancreatitis patients
Based on the four segments and treatment by syndrome differentiation to lower the mortality of sepsis
相关作者
暂无数据
相关机构
Department of General Surgery, First Affiliated Hospital, Dalian Medical University
School of Medicine, Nanjing University Nanjing
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University
Department of Integrative Medicine, West China Hospital, Sichuan University
Emergency Department of Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine