Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ

Cheng Mingliang; Wu Yayun; Huang Kefu; Luo Tianyong; Ding Yisheng; Lu Yinying; Liu Rencai; Wu Jun

doi:10.1007/BF02934181

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Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ

OriginalPaper | Updated：2021-08-27

- Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ
- Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ
- 中国结合医学杂志（英文版） 1999年5卷第1期页码：16-19
- Affiliations：
  
  Department of Infectious Disease, Affiliated Hospital of Guiyang Medical College,Guiyang
- Author bio：
- Funds：
  
  Δ;Supported by the ”8.5” key project of scientific commission of Guizhou province (1993 No. 2037) and the ”9. 5” brainstormed project of scientific commission of Guizhou province. (1996 No. 1028)
- DOI：10.1007/BF02934181
  中图分类号：
- 纸质出版日期：1999，
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Mingliang, C., Yayun, W., Kefu, H. et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ, ., CJIM 5, 16–19 (1999). https://doi.org/10.1007/BF02934181

Cheng Mingliang, Wu Yayun, Huang Kefu, et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ[J]. Chinese Journal of Integrative Medicine, 1999,5(1):16-19.
Mingliang, C., Yayun, W., Kefu, H. et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ, ., CJIM 5, 16–19 (1999). https://doi.org/10.1007/BF02934181 DOI：

Cheng Mingliang, Wu Yayun, Huang Kefu, et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ[J]. Chinese Journal of Integrative Medicine, 1999,5(1):16-19. DOI： 10.1007/BF02934181.

摘要

Objective: To find the effective method of curing liver fibrosis of hepatitis B.Methods: Using interferon-α1 (IFN-α1) and traditional Chinese medicine (TCM) preparation to treat the patients with liver fibrosis of hepatitis B and observe the changes of indexes including levels of laminin

precollagen type III

hyaluronic acid

liver puncture

ultrasonography and fibergastroscopy before and after treatment.Results: After 3 months treatment

the indexes were lower than those before treatment. There was a significant difference (P < 0.01). Liver biopsy

ultrasonography and fiber-gastroscopy proved that the liver fibrosis was improved. After 6 months the indexes of the hepatofibrosis

blood albumin and globulin levels showed that the differences between the IFN-effective group and the IFN-ineffective group was significant (P < 0.001).Conclusion: Beneficial effect might be obtained by using IFN-cq to suppress the replication of hepatitis B virus and TCM preparation to treat liver fibrosis.

Abstract

precollagen type III

hyaluronic acid

liver puncture

ultrasonography and fibergastroscopy before and after treatment.Results: After 3 months treatment

the indexes were lower than those before treatment. There was a significant difference (P < 0.01). Liver biopsy

ultrasonography and fiber-gastroscopy proved that the liver fibrosis was improved. After 6 months the indexes of the hepatofibrosis

关键词

hepatitis BhepatofibrosisinterferonChinese medical preparationliver biopsylaminin

Keywords

hepatitis BhepatofibrosisinterferonChinese medical preparationliver biopsylaminin

references

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Billiau A. The model of action of interferons in viral infections and their possible role in the control of hepatitis B. J Hepatol 1986; 3 (suppl 2): S171.

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