To study the pharmacological effect of Xiaoke Granule on blood sugar and blood rheological property in the diabetic animals. Alloxan induced diabetic mice or rats were grouped randomly. The effects of XKG on blood sugar

appetite

capacity of drinking

glucose tolerance

blood lipid and blood rheological property were observed and compared among groups. XKG showed a trend in reducing the appetite and capacity of drinking

increasing the body weight

and significantly inhibiting the increase of blood sugar coused by ectogenic glucose in mice

and could improve the blood lipid and blood rheological property in rats. XKG is effective in reducing serum total cholesterol

lowering the blood viscosity

improving the blood rheological property of alloxan induced diabetic animals. Therefore

it might effective in treating and preventing the occurrence of diabetes mellitus and the complications of blood stasis.