Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients

Hui-Wen Liu; Tie-Zhang Zhang; Guang-Wei Li; Ya-Yun Jiang

doi:10.1007/BF02935014

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Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients

OriginalPaper | Updated：2021-08-27

- Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients
- Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients
- 中国结合医学杂志（英文版） 2001年7卷第2期页码：107-110
- Affiliations：
  
  1. Japan Friendship Hospital, Beijing,Beijing,China
  2. General Hospital of Daqing Petroleum,Heilongjiang
- Author bio：
- Funds：
- DOI：10.1007/BF02935014
  中图分类号：
- 纸质出版日期：2001，
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Liu, HW., Zhang, TZ., Li, GW. et al. Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients., CJIM 7, 107–110 (2001). https://doi.org/10.1007/BF02935014

Hui-Wen Liu, Tie-Zhang Zhang, Guang-Wei Li, et al. Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients[J]. Chinese Journal of Integrative Medicine, 2001,7(2):107-110.
Liu, HW., Zhang, TZ., Li, GW. et al. Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients., CJIM 7, 107–110 (2001). https://doi.org/10.1007/BF02935014 DOI：

Hui-Wen Liu, Tie-Zhang Zhang, Guang-Wei Li, et al. Study on the relationship between insulin-resistance and syndrome differentiation typing in hypertension patients[J]. Chinese Journal of Integrative Medicine, 2001,7(2):107-110. DOI： 10.1007/BF02935014.

摘要

Objective:To find the relationship between insulin-resistance and Syndrome Differentiation type (SDT) in hypertensive patients.Methods: Two hundred and nine patients of early stage hypertention with no complications of heart

brain or kidney were selected and classified into 4 types according to SDT

the Liver-Fire exuberant type (A)

the Phlegm-Dampness abundant type (B)

the Yin-Deficiency and Yang-Excess type (C) and the Deficiency of both Yin and Yang type (D). Their insulin sensitivity was examined and compared with that of 40 healthy subjects.Results: (1) Compared with the healthy subjects

all hypertensive patients had apparent insulin resistance (P<0.05). If the insulin sensitivity of healthy subjects was defined as 1.00

that of patients of type A

C and D were 0.54

0.58

0.65 and 0.80 respectively. (2 ) The insulin sensitivity of patients in the 4 SDT groups were compared and no significant difference was found in comparison between group A

B and C

while significant difference was found when the other three groups were compared with group D (P<0.05)

the insulin sensitivity of type D was close to that of the healthy subjects. (3) The fasting blood insulin of type D was obviously lower and the insulin sensitivity of type D was obviously higher than that of the other three types as a whole (P=0.0001). (4) Multivariate regression analysis demonstrated that insulin sensitivity was closely correlated with SDT (P=0.0001).Conclusion: Insulin resistance is one of the pathological basis for SDT in hypertension.

Abstract

brain or kidney were selected and classified into 4 types according to SDT

the Liver-Fire exuberant type (A)

the Phlegm-Dampness abundant type (B)

all hypertensive patients had apparent insulin resistance (P<0.05). If the insulin sensitivity of healthy subjects was defined as 1.00

that of patients of type A

C and D were 0.54

0.58

0.65 and 0.80 respectively. (2 ) The insulin sensitivity of patients in the 4 SDT groups were compared and no significant difference was found in comparison between group A

B and C

while significant difference was found when the other three groups were compared with group D (P<0.05)

关键词

hypertensionTraditional Chinese MedicineSyndrome Differentiation typinginsulin resistanceInsulin Sensitivity

Keywords

hypertensionTraditional Chinese MedicineSyndrome Differentiation typinginsulin resistanceInsulin Sensitivity

references

Reaven Gm. Role of insulin resistance in human disease. Diabetes, 1988, 37:1595.

Chen Hz, edit. Practical Internal Medicine (10th edition) Beijing: People’s Healthing Publishing House 1997:1283.

Guidance on Principle of Clinical Research of Chinese New Drugs (trial). Vol. 1.1993 : 28 (promulgated by Ministry of Health, PRC).

Li Gw, Pan Rr, Lillio Ja, et al., A new index of determining insulin-sensitivity among people. J Chin Internal Medicine 1993:32 (11): 656.

Suislocri A. Insulin resistance and hypertension. Am J Med Sci 1990:300:104.

Kannel Wb, Wilson Wf, Zheng Tj. The epidemiology of impaired glucose tolerance and hypertension. Am Heart J 1991;121:1268–1273.

Liu Gz, Gao Rl, Li Gw, et al. Summary of National Meetings on Hypertension, Coronary Heart Diseases and Diabetes. J China Cardiovascular Diseases 1993; 21(4):260.

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