Objective: To study the clinical effect of Taozhi Zhipu Mixture(

TZM) in preventing postoperative intestinal adhesion.Methods: The total of 396 patients who had received abdominal operation were randomly divided into the treated group (188 cases) and the control group (208 cases). Same treatment was given to both groups except that the treated group received TZM orally or via nasogastric tube. The time of borborygmus recovering and first passing of flatus-defecation after operation was recorded. Patients’ gastro-intestinal motility was observed by isotope tracing with I131 capsule. The frequency and intensity of borborygmus were measured by a tracer. All patients had been followed up for 2-3 years.Results: The recovery of borborygmus

the first passing of flatus-defecation were much earlier

the I131 capsule passed gastro-intestinal tract more quickly

and the tracer showed higher frequency and intensity of borborygmus in the treated group than those in the control group. Follow-up study also showed the treated group was better than the control group in the non-adhesion rate and the total effective rate (P < 0.05).Conclusion: TZM has good effect on stimulating postoperational gastro-intestinal peristalsis and preventing the occurrence of postoperational intestinal adhesion.