Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats

Song Xianwen; Shen Peizhi; Shi Yinyu

doi:10.1007/BF02935175

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Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats

OriginalPaper | Updated：2021-08-27

- Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats
- Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats
- 中国结合医学杂志（英文版） 1999年5卷第3期页码：205-208
- Affiliations：
  
  1. Affiliated Ganquan Hospital of Shanghai Railway University,Shanghai
  2. Shanghai Academy of Traditional Chinese Medicine,Shanghai
  3. Shuguang Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai
- Author bio：
- Funds：
- DOI：10.1007/BF02935175
  中图分类号：
- 纸质出版日期：1999，
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Xianwen, S., Peizhi, S. & Yinyu, S. Effect of Kidney Tonifying Migu Tablet () on osteoporosis rats) on osteoporosis rats., CJIM 5, 205 (1999). https://doi.org/10.1007/BF02935175

Song Xianwen, Shen Peizhi, Shi Yinyu. Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats[J]. Chinese Journal of Integrative Medicine, 1999,5(3):205-208.
Xianwen, S., Peizhi, S. & Yinyu, S. Effect of Kidney Tonifying Migu Tablet () on osteoporosis rats) on osteoporosis rats., CJIM 5, 205 (1999). https://doi.org/10.1007/BF02935175 DOI：

Song Xianwen, Shen Peizhi, Shi Yinyu. Effect of Kidney Tonifying Migu Tablet ( ) on osteoporosis rats) on osteoporosis rats[J]. Chinese Journal of Integrative Medicine, 1999,5(3):205-208. DOI： 10.1007/BF02935175.

摘要

Objective: To observe the effect of Kidney tonic

the Migu Tablet ( ) on bone and endocrine of osteoporosis rats.Methods: Two stages were divided

stage 1: Using ovariectomy to establish the osteoporosis rat model; stage 2: Treating the model;Results: After 3 months treatment with MGT

which can prevent the lowering of femur bone density

tibia trabecular volume and femur bending resistant strength

but was unable to raise those lowered parameters. Serum corticosterone determination showed that the Kidney tonic could regulate the secretion of estrogen and testosterone

adjust the imbalance of E2/T ratio.Conclusions: MGT

a Kidney tonic could prevent and treat experimental osteoporosis

its imbalance of E2/T ratio adjustment is possibly one of the mechanisms to lessen the patient’s Kidney deficiency.

Abstract

Objective: To observe the effect of Kidney tonic

the Migu Tablet ( ) on bone and endocrine of osteoporosis rats.Methods: Two stages were divided

stage 1: Using ovariectomy to establish the osteoporosis rat model; stage 2: Treating the model;Results: After 3 months treatment with MGT

which can prevent the lowering of femur bone density

tibia trabecular volume and femur bending resistant strength

but was unable to raise those lowered parameters. Serum corticosterone determination showed that the Kidney tonic could regulate the secretion of estrogen and testosterone

adjust the imbalance of E2/T ratio.Conclusions: MGT

a Kidney tonic could prevent and treat experimental osteoporosis

its imbalance of E2/T ratio adjustment is possibly one of the mechanisms to lessen the patient’s Kidney deficiency.

关键词

OsteoporosisboneCorticosteroneChinese medicinal herbsrats

Keywords

OsteoporosisboneCorticosteroneChinese medicinal herbsrats

references

Bar Shira Maymon B, Coleman R, Cohen A, et al. Age-related bone loss in lumbar vertebrae of CW-1 female mice: A histomorphometric study. Calcif Tissue Int 1989; 44: 36–45.

Kalu DN. The ovariectomized rat model of postmenopausal bone loss. Bone and Mineral 1991; 15: 175–192.

Kalu DN, Lin CC, Hardin RR, et al. The aged rat model of ovarian hormone deficiency bone loss. Endocrinology 1989; 124:7–16.

1989; 9(6): 331–334.

Body JJ, Struelens M, Borkowsk A, et al. Effects of estrogens and calcium on calcium secretion in postmenopausal women. J Clin Endocrinol Metab 1989; 68:223–228.

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