Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency

Gao Hu-bin; Yu Zhong-yuan; Qiu Xin-hai; Tian Song; Guo Geng-xin; Li Wei; Hu Xiao-mei; Liu Li; Li Xin; He Hong

doi:10.1007/BF02940695

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Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency

OriginalPaper | Updated：2021-08-27

- Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency
- Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency
- 中国结合医学杂志（英文版） 1995年1卷第4期页码：272-274
- Affiliations：
  
  Kidney Division, People Hospital, Beijing Medical University,Beijing
- Author bio：
- Funds：
- DOI：10.1007/BF02940695
  中图分类号：
- 纸质出版日期：1995，
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Gao, Hb., Yu, Zy., Qiu, Xh. et al. Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency., CJIM 1, 272 (1995). https://doi.org/10.1007/BF02940695

Gao Hu-bin, Yu Zhong-yuan, Qiu Xin-hai, et al. Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency[J]. Chinese Journal of Integrative Medicine, 1995,1(4):272-274.
Gao, Hb., Yu, Zy., Qiu, Xh. et al. Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency., CJIM 1, 272 (1995). https://doi.org/10.1007/BF02940695 DOI：

Gao Hu-bin, Yu Zhong-yuan, Qiu Xin-hai, et al. Effects of oenethera biennis oil on plasma lipid, thromboxane A2 and angiotensin II of chronic renal insufficiency[J]. Chinese Journal of Integrative Medicine, 1995,1(4):272-274. DOI： 10.1007/BF02940695.

摘要

Oenethera biennis oil was administered (6 g per day) in 23 chronic renal insufficiency patients over a 4 week period. Changes of serum creatinine

creatinine clearance

plasma lipid

renin activity

and angiotensin II

urinary thromboxane B2 and 6-keto-prostaglandin F1α were observed before and after the treatment. Results showed that after treatment

the creatinine clearance increased

serum total cholesterol

triglyceride and low density lipoprotein decreased

high density lipoprotein increased

plasma renin activity

angiotensin II and urinary thromboxane B2 decreased significantly. The conclusion was that Oenethera biennis oil could improve the pathological process of renal diseases

and has beneficial effects on plasma lipid disorder and glomerular hemodynamics.

Abstract

Oenethera biennis oil was administered (6 g per day) in 23 chronic renal insufficiency patients over a 4 week period. Changes of serum creatinine

creatinine clearance

plasma lipid

renin activity

and angiotensin II

urinary thromboxane B2 and 6-keto-prostaglandin F1α were observed before and after the treatment. Results showed that after treatment

the creatinine clearance increased

serum total cholesterol

triglyceride and low density lipoprotein decreased

high density lipoprotein increased

plasma renin activity

angiotensin II and urinary thromboxane B2 decreased significantly. The conclusion was that Oenethera biennis oil could improve the pathological process of renal diseases

and has beneficial effects on plasma lipid disorder and glomerular hemodynamics.

关键词

Oenethera biennis oilchronic renal insufficiencycreatinine clearanceplasma renin activityangiotensin IIthromboxane6-keto-prostaglandin F1α

Keywords

Oenethera biennis oilchronic renal insufficiencycreatinine clearanceplasma renin activityangiotensin IIthromboxane6-keto-prostaglandin F1α

references

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Harris KPG. Lovastatin Ameliorates the Development of Glomerulosclerosis and Uremia on Experimental Nephrotic Syndrome. Am J Kidney Dis 1990;15:16.

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Barcelli UO, et al. High Linoleic Acid Diets Ameliorate Diabetic Nephropathy in Rats. Am J Kidney Dis 1990;16:244.

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Barcelli UO, et al. Beneficial Effects of Polyunsaturated Fatty Acids in Partially Nephrectomized Rats. Prostaglandins 1986;32:211.

Papanikolaou N. Alteration of Mercuric Chloride Induced Autoimmune Glomerulonephritis in Brown-Norway Rats by Herring Oil, Evening Primrose Oil and Oky-046 a Selective TXA-Synthetase Inhibitor. Prostaglandins Leukot Essent Fatty Acids 1987;27:29.

Welch WJ, et al. Feed Back Responses during Sequential Inhibition of Angiotensin and Thromboxane. Am Physiol Society 1990;363:457–466.

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