Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats

Lin Ping; Yasuhiro Mizoguzhi; Seiji Morisawa

doi:10.1007/BF02940702

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Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats

OriginalPaper | Updated：2021-08-27

- Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats
- Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats
- 中国结合医学杂志（英文版） 1995年1卷第4期页码：291-293
- Affiliations：
  
  1. Liver Diseases Research Center, Shanghai Academy of Traditional Chinese Medicine,Shanghai
  2. Division of biochemistry, Department of Medicine, Osaka City University,Japan
- Author bio：
- Funds：
- DOI：10.1007/BF02940702
  中图分类号：
- 纸质出版日期：1995，
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Lin, P., Yasuhiro, M. & Seiji, M. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats., CJIM 1, 291–293 (1995). https://doi.org/10.1007/BF02940702

Lin Ping, Yasuhiro Mizoguzhi, Seiji Morisawa. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats[J]. Chinese Journal of Integrative Medicine, 1995,1(4):291-293.
Lin, P., Yasuhiro, M. & Seiji, M. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats., CJIM 1, 291–293 (1995). https://doi.org/10.1007/BF02940702 DOI：

Lin Ping, Yasuhiro Mizoguzhi, Seiji Morisawa. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats[J]. Chinese Journal of Integrative Medicine, 1995,1(4):291-293. DOI： 10.1007/BF02940702.

摘要

Treated the experimental acute liver injury rat induced by D-galactosamine with magnesium lithosperamate-B could significantly lower the serum activity of alanine transaminase and aspartate aminotransferase

relieve the necrosis of hepatocytes and elevate the levels of products of arachidonic acid (6-ke-to-prostaglandin 1α

prostaglandin D2 and the total prostaglandin) in liver. These results suggested that magnesium lithosperamate B was one of the main components ofSalvia miltiorrzae in treating liver injury

the action on elevating the total prostaglandin in liver might be its mechanism.

Abstract

relieve the necrosis of hepatocytes and elevate the levels of products of arachidonic acid (6-ke-to-prostaglandin 1α

prostaglandin D2 and the total prostaglandin) in liver. These results suggested that magnesium lithosperamate B was one of the main components ofSalvia miltiorrzae in treating liver injury

the action on elevating the total prostaglandin in liver might be its mechanism.

关键词

Radix Salviae Miltiorrhizaemagnesium lithosperamate BD-galactosamineliver injuryprostaglandin

Keywords

Radix Salviae Miltiorrhizaemagnesium lithosperamate BD-galactosamineliver injuryprostaglandin

references

Tanka T, et al. Magnesium and ammonium-potassium lithospermates, the active principles having a ureria-preventive effect from Salvia miltiorrhiza. Chem Pharm Bull 1989;37:340.

Yokozawa T, et al. Effect of magnesium lithospermate B on urinary prostaglandins in rats with renal failure. J Natural Products 1990; 53:662.

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