Study of effects ofCordyceps sinensis on natural killer cells in leukemia

Liu Chao; Lu Shan; Ji Mei-rong; Xie Yi

doi:10.1007/BF02942760

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Study of effects ofCordyceps sinensis on natural killer cells in leukemia

OriginalPaper | Updated：2021-08-27

- Study of effects ofCordyceps sinensis on natural killer cells in leukemia
- Study of effects ofCordyceps sinensis on natural killer cells in leukemia
- 中国结合医学杂志（英文版） 1995年1卷第2期页码：108-110
- Affiliations：
  
  Hematology Research Unit, Huashan Hospital, Shanghai Medical University,Shanghai
- Author bio：
- Funds：
- DOI：10.1007/BF02942760
  中图分类号：
- 纸质出版日期：1995，
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Liu, C., Lu, S., Ji, Mr. et al. Study of effects ofCordyceps sinensis on natural killer cells in leukemia., CJIM 1, 108–110 (1995). https://doi.org/10.1007/BF02942760

Liu Chao, Lu Shan, Ji Mei-rong, et al. Study of effects ofCordyceps sinensis on natural killer cells in leukemia[J]. Chinese Journal of Integrative Medicine, 1995,1(2):108-110.
Liu, C., Lu, S., Ji, Mr. et al. Study of effects ofCordyceps sinensis on natural killer cells in leukemia., CJIM 1, 108–110 (1995). https://doi.org/10.1007/BF02942760 DOI：

Liu Chao, Lu Shan, Ji Mei-rong, et al. Study of effects ofCordyceps sinensis on natural killer cells in leukemia[J]. Chinese Journal of Integrative Medicine, 1995,1(2):108-110. DOI： 10.1007/BF02942760.

摘要

The effects ofCordyceps sinensis (CS) on peripheral natural killer cells from healthy subjects and from leukemia patients were studied. The results showed CS could augment natural killer cell activity. The dose-dependent effect was found within the range of the dosage adopted for the tests (r=0.984

P<0.01; r=0.988

P<0.01). Furthermore

the results suggested CS could also improve CD16 marker expression on the surface of lymphocytes and the binding capacity of K562 cells. Cytotoxicity was not present when the peripheral blood mononuclear cells were co-incubated with CS. These results suggested CS could be exploited and utilized as a biological response modifier in the treatment of leukemia.

Abstract

P<0.01; r=0.988

P<0.01). Furthermore

关键词

acute leukemiaCordyceps sinensisnatural killer cells

Keywords

acute leukemiaCordyceps sinensisnatural killer cells

references

Sorskaar D, et al. Increased natural killer cell activity and numbers of leu-7 and leu-11b (CD16) positive cells in bone marrow of children in remission from acute lymphoblastic leukemia. Scand J Immuno 1989;29(1):65.

Gabrilovac J, et al. Defects of natural killer cell activity in children with untreated acute lymphocyte leukemia. Klnn Wochenschr 1988; 66(8):354.

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