Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice

Bingkuang Zhu; Li Sun; Shifu Zheng; Ronghua Zhang

doi:10.1007/BF02947382

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Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice

OriginalPaper | Updated：2021-08-27

- Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice
- Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice
- 中国结合医学杂志（英文版） 2000年6卷第4期页码：283-286
- Affiliations：
  
  1. The First Hospital of Medical College, Jinan University,Guangzhou
  2. Medical College, Jinan University,Guangzhou
- Author bio：
- Funds：
  
  This study was funded by Overseas Chinese Affairs Office of the State Council (No. 93-95-47)
- DOI：10.1007/BF02947382
  中图分类号：
- 纸质出版日期：2000，
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Zhu, B., Sun, L., Zheng, S. et al. Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice., CJIM 6, 283–286 (2000). https://doi.org/10.1007/BF02947382

Bingkuang Zhu, Li Sun, Shifu Zheng, et al. Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice[J]. Chinese Journal of Integrative Medicine, 2000,6(4):283-286.
Zhu, B., Sun, L., Zheng, S. et al. Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice., CJIM 6, 283–286 (2000). https://doi.org/10.1007/BF02947382 DOI：

Bingkuang Zhu, Li Sun, Shifu Zheng, et al. Experimental study of yishou tiaozhi tablet on free radical metabolism in aging model mice[J]. Chinese Journal of Integrative Medicine, 2000,6(4):283-286. DOI： 10.1007/BF02947382.

摘要

Objective: To observe the effect of Yishou Tiaozhi tablet (YSTZT) on the metabolism of free radical in mice of aging model.Methods: Using the aging model induced by hypodermic injection of 5% Dglalactose in mice for forty days. The content of malondialdehyde(MDA) and activity of Superoxide dismutase (SOD)

glutathione peroxidase (GSH-Px) in serum

activity of monoamine oxidase B (MAO-B)

Na+-K+-ATPase in brain were investigated after treatment.Results: Compared with the aging model group

it showed that YSTZT could obviously inhibit the increase of level of MDA in serum and the activities of MAO-B in brain; and enhance the activities of SOD

GSH-Px in serum

and the activities of Na+ -K+ -ATPase in brain. Furthermore

YSTZT could obviously elevate the tolerance to fatigue and hypoxia in mice.Conclusion: YSTZT could effectively improve the free radical metabolism of senile body

it is an ideal and effective medicine in preventing aging

which is also one of the experimental basis in proving the theory of ”Spleen and Kidney Deficiency complicated with Stasis and Phlegm causes aging”.

Abstract

glutathione peroxidase (GSH-Px) in serum

activity of monoamine oxidase B (MAO-B)

Na+-K+-ATPase in brain were investigated after treatment.Results: Compared with the aging model group

it showed that YSTZT could obviously inhibit the increase of level of MDA in serum and the activities of MAO-B in brain; and enhance the activities of SOD

GSH-Px in serum

and the activities of Na+ -K+ -ATPase in brain. Furthermore

YSTZT could obviously elevate the tolerance to fatigue and hypoxia in mice.Conclusion: YSTZT could effectively improve the free radical metabolism of senile body

it is an ideal and effective medicine in preventing aging

which is also one of the experimental basis in proving the theory of ”Spleen and Kidney Deficiency complicated with Stasis and Phlegm causes aging”.

关键词

Yishou Tiaozhi tabletaging modelfree radical

Keywords

Yishou Tiaozhi tabletaging modelfree radical

references

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Gong GQ, Xu FB. Research on mice aging model. Journal of the China Pharmaceutical University. 1991; 22(2): 101–103.

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Qu YH, Zhang LT, Mei JJ. Analysing TCM mechanism of aging-On comprehesive sthenia and asthenia factors of aging. Journal of Basic Theory of Traditional Chinese Medicine. 1996; 2(1):27, 61.

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Fang YQ. Exploration on the research way of Sputum Syndrome. Journal of Basic Theory of Traditional Chinese Medicine. 1996; 2(6):20–23.

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