Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats

Jin Chu; Bin Li; Lin Li; Cuifei Ye; Huibo Liu; Shida He

doi:10.1007/BF02947383

Your Location：

Home >

Browse articles >

Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats

OriginalPaper | Updated：2021-08-27

- Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats
- Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats
- 中国结合医学杂志（英文版） 2000年6卷第4期页码：287-289
- Affiliations：
  
  Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science,Beijing
- Author bio：
- Funds：
  
  This study was funded by Scientific Committee of Beijing (No. 951890600) and State Ministry of Personnel(No.l998)
- DOI：10.1007/BF02947383
  中图分类号：
- 纸质出版日期：2000，
Scan for full text
Chu, J., Li, B., Li, L. et al. Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats., CJIM 6, 287–289 (2000). https://doi.org/10.1007/BF02947383

Jin Chu, Bin Li, Lin Li, et al. Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats[J]. Chinese Journal of Integrative Medicine, 2000,6(4):287-289.
Chu, J., Li, B., Li, L. et al. Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats., CJIM 6, 287–289 (2000). https://doi.org/10.1007/BF02947383 DOI：

Jin Chu, Bin Li, Lin Li, et al. Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats[J]. Chinese Journal of Integrative Medicine, 2000,6(4):287-289. DOI： 10.1007/BF02947383.

摘要

Objective: To investigate the effect of compound 962 capsule (abbre. as 962) on liver lipid peroxidation and indexes of thymus and spleen in aged rats.Methods: Rats were divided into young control

aged model

Piracetam

962 middle dose (0.9 g/kg) and high dose (1.8 g/kg) groups. All test drugs were administrated for 1 month by gastrogavage. The liver lipid peroxidation was determined by thiobarbituric (TBA) method. The thymus index and spleen index were determined by weighing method.Results: 962 (middle and high dose) attenuated liver lipid peroxidation

increased the thymus index of aged rats. There was no effect on spleen index in all drug-treated groups.Conclusion: 962 could decrease liver lipid peroxidation and increase thymus index. It suggested that 962 might be beneficial in retarding aging process.

Abstract

Objective: To investigate the effect of compound 962 capsule (abbre. as 962) on liver lipid peroxidation and indexes of thymus and spleen in aged rats.Methods: Rats were divided into young control

aged model

Piracetam

关键词

traditional Chinese compoundagingliver lipid peroxidationthymus indexspleen index

Keywords

traditional Chinese compoundagingliver lipid peroxidationthymus indexspleen index

references

Meng QL. Relationship between lipid peroxide and aging. Chin J Geriatrics 1987;6(4): 242–243.

Halliwell B. Lipid peroxidation, oxygen radicals, cell damage and antioxydant therapy. Lancet 1984; (1):1396–1397.

Chen Y, Zhou M. Lipid peroxidation and disease. National Medical J of China 1985;65(11):704–706.

Li B, Li L, Li ZX, et al. Effect of Bushen Jiannao No. 1 Mixture on learning and memory functions and anti-fatigue ability in mice. Chin J Chinese Materia Medica 1999;24(2):104–106.

Liu HB, Li L, Li B, et al. Application of orthogonalt value method in analyzing the primary drugs in compound 961, a traditional Chinese medicine. Chin J Clin Pharmacology and Therapeutics 1998;3(2):89–91.

Zhang QL, Yu QM. Effect of compound Radix Polygoni Multiflori on plasma lipid peroxide in rats. In CHEN Qi edit. Pharmacologic Research Methods of Traditional Chinese Herbs. Beijing: People’s Health Publishing House, 1993: 940–943.

Hang BQ, Dai Y. Effect of Ligustrum Lucidum on thymus and spleen weight of rats. In LI Yikui edit. Experimental Pharmacology Research Methods of Traditional Chinese Herbs. Shanghai: Shanghai Science and Technology Press, 1994:779–780.

Qian YK, Zhang GX. Immunological research of senility. In KUANG Ankun edit. Geriatrics in China. Changsha: Hunan Technology and Science Press, 1989: 116–121.

Zhou Y. Pharmacological research method of restoratives. In CHEN Qi edit. Pharmacological Research Methods of Traditional Chinese Herbs. Beijing: People’s Health Publishing House, 1993:712–713.

FULL TEXT LINK

More>

浏览量

356

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Characteristics of lymphocyte nuclear factor-κB signal transduction kinase expression in aging process and regulatory effect of epimedium flavonoids

Happy aging

Protection of acanthopanax senticosus saponin on free radical injury induced aging of nerve cell

Effect of cistanche desertica polysaccharides on learning and memory functions and infrastructure of cerebral neurons in experimental aging mice

Comparative study on immunologic effect of Composite Prescriptions of tonifying kidney, invigorating Spleen and promoting blood circulation drugs in mice