Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance

Liqun Zhu; Hongying LI; Yinghua Liu

doi:10.1007/BF02950924

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Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance

OriginalPaper | Updated：2021-08-27

- Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance
- Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance
- 中国结合医学杂志（英文版） 2000年6卷第3期页码：192-195
- Affiliations：
  
  1. The First Central Hospital, Institute of Endocrinology, Tianjin Medical University,Tianjin
  2. Hospital of Traditional Chinese Medicine of Heping District,Tianjin
- Author bio：
- Funds：
- DOI：10.1007/BF02950924
  中图分类号：
- 纸质出版日期：2000，
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Zhu, L., LI, H. & Liu, Y. Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance., CJIM 6, 192–195 (2000). https://doi.org/10.1007/BF02950924

Liqun Zhu, Hongying LI, Yinghua Liu. Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance[J]. Chinese Journal of Integrative Medicine, 2000,6(3):192-195.
Zhu, L., LI, H. & Liu, Y. Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance., CJIM 6, 192–195 (2000). https://doi.org/10.1007/BF02950924 DOI：

Liqun Zhu, Hongying LI, Yinghua Liu. Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance[J]. Chinese Journal of Integrative Medicine, 2000,6(3):192-195. DOI： 10.1007/BF02950924.

摘要

Objective: To study the therapeutic effect of Chinese herbal medicine (CHM) for supplementing Qi

activating blood circulation and tonifying Kidney on prevention and treatment of diabetes in middle and aged women with Kidney Deficiency and bone metabolic disturbance.Methods: Clinical observation was taken in 52 patients

who were divided into two groups

the control group (treated with hypoglycemic agent alone) and the treated group (treated with hypoglycemic agent and CHM).Results: Before treatment

patients in both groups showed obviously higher blood alkaline phosphatase

β2-microglobulin (β2-MG) level

urinary β2-MG

calcium and phosphorus level

but lower serum estradiol level than those in normal subjects. After 3 months’ treatment

no apparent change in serum estradiol level was observed

but other parameters were all lowered obviously in the two groups

with the changes revealed more obviously in the treated group. The symptoms of Kidney Deficiency

such as lumbodorsal pain

fatigue

palpitation and vertigo

were improved after treatment

which was also more obviously in the treated group.Conclusion: CHM for supplementing Qi

activating blood circulation and tonifying Kidney was effective in improving Kidney Deficiency and mineral substance loss in bones in middle and aged diabetic women patients. The CHM and western drugs acted synergistically.

Abstract

Objective: To study the therapeutic effect of Chinese herbal medicine (CHM) for supplementing Qi

who were divided into two groups

the control group (treated with hypoglycemic agent alone) and the treated group (treated with hypoglycemic agent and CHM).Results: Before treatment

patients in both groups showed obviously higher blood alkaline phosphatase

β2-microglobulin (β2-MG) level

urinary β2-MG

calcium and phosphorus level

but lower serum estradiol level than those in normal subjects. After 3 months’ treatment

no apparent change in serum estradiol level was observed

but other parameters were all lowered obviously in the two groups

with the changes revealed more obviously in the treated group. The symptoms of Kidney Deficiency

such as lumbodorsal pain

fatigue

palpitation and vertigo

were improved after treatment

which was also more obviously in the treated group.Conclusion: CHM for supplementing Qi

关键词

middle and aged womendiabetes mellitusKidney Deficiencybone metabolism disturbanceintegration of traditional Chinese and western medicine

Keywords

middle and aged womendiabetes mellitusKidney Deficiencybone metabolism disturbanceintegration of traditional Chinese and western medicine

references

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Liu DG, YE EM, Hou ZK, et al. Exploration on replenishing Kidney and regulating ovarian function—analysis of 56 cases. CJIM 1984;4(8): 476–477.

Wei JA, Chen XH, LI CJ, et al. The effect of Shenxu Gutong capsule on the bone density of menopausal women. J of TCM 1995;36(9):548–550.

Zhang XQ, Guo SS. Survey of clinical application of tonifying Kidney and activating blood circulation. CJIM 1994;14(6):376–378.

Kuang AK. Chief Editor. Handbook of internal medicine. 3rd Edition. Shanghai: Shanghai Press of Science and Technology, 1990: 667–669.

Shi JR, Jia SY. Handbook of clinical examination. Jinan: Shandong Press of Science and Technology, 1988: 764–765, 773–776.

Zhu LQ, Liu YH, Wang WZ. Observation on HbA1c, TXB2, 6-Keto-PGF1 α of diabetic patients before and after integrated treatment. New TCM and Pharmacology 1998; 30(3):40–42.

Shen L, DU JY, Yang BY, et al. Clinical study on the bone material lose of post menopausal women with tonifying Kidney principle. CJIM 1994;14(9):515–518.

LI QN, WU T, Xie H, et al. The effect of Epimedium extract on the bone metabolism of castrated rats. Chin Herb Med 1993; 24(12): 637- 638, 658.

Lin YY, Chen YS, Han XM, et al. The effect of warming Yang herbs on the uteroestrogen receptor of hypothalamas-pitutiary-adrenal cortex axis inhibited rats model. CJIM 1985;5(3): 175–177.

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