Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans

Shangzhu LI; Pingping Huang; Chunhua Liu; Shugei Wang; Guanqing Qian

doi:10.1007/BF02950939

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Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans

OriginalPaper | Updated：2021-08-27

- Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans
- Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans
- 中国结合医学杂志（英文版） 2000年6卷第3期页码：228
- Affiliations：
  
  Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin
- Author bio：
- Funds：
- DOI：10.1007/BF02950939
  中图分类号：
- 纸质出版日期：2000，
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Shangzhu, L., Pingping, H., Chunhua, L. et al. Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans., CJIM 6, 228 (2000). https://doi.org/10.1007/BF02950939

Shangzhu LI, Pingping Huang, Chunhua Liu, et al. Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans[J]. Chinese Journal of Integrative Medicine, 2000,6(3):228.
Shangzhu, L., Pingping, H., Chunhua, L. et al. Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans., CJIM 6, 228 (2000). https://doi.org/10.1007/BF02950939 DOI：

Shangzhu LI, Pingping Huang, Chunhua Liu, et al. Effect of ligustrazine injection on vascular endothelial cell of the patients with arteriosclerosis obliterans[J]. Chinese Journal of Integrative Medicine, 2000,6(3):228. DOI： 10.1007/BF02950939.

摘要

Objective: To study the effect of ligustrazine injection (LI) on vascular endothelial cell of the patients with arteriosclerosis obliterans (ASO) and explore the new pathway of investigating effective vascular protective agents in Chinese medicinal herbs.Methods: Forty-six patients with ASO in the LI group treated by LI were observed

their circulating endothelial cells (CEC) were detected quantitatively before and after treatment. The results were compared with the CEC of 53 cases of healthy persons (control group) in the same period.Results: In the LI group

the immediate cure rate was 45. 7% (21 cases)

markedly effective rate 36.9% (17 cases) and the effective rate 17.4% (8 cases). The CEC of patients before treatment was 4. 39 ± 1. 76/0. 9μl

which was significantly higher than that of the healthy persons (1. 53 ± 0. 42/0. 9μl). It could be reduced after treatment

along with the improvement of symptoms and signs

to 2.43 ± 0.87/0.9μl

P<0.01.Conclusion: LI in treating ASO not only displays extraordinary effect

but also has good effect in curing the damage of endothelial cells.

Abstract

the immediate cure rate was 45. 7% (21 cases)

markedly effective rate 36.9% (17 cases) and the effective rate 17.4% (8 cases). The CEC of patients before treatment was 4. 39 ± 1. 76/0. 9μl

which was significantly higher than that of the healthy persons (1. 53 ± 0. 42/0. 9μl). It could be reduced after treatment

along with the improvement of symptoms and signs

to 2.43 ± 0.87/0.9μl

P<0.01.Conclusion: LI in treating ASO not only displays extraordinary effect

but also has good effect in curing the damage of endothelial cells.

关键词

Vascular Endothelial CellEffective RateHealthy PersonChinese Medicinal HerbPeking Union Medical College

Keywords

Vascular Endothelial CellEffective RateHealthy PersonChinese Medicinal HerbPeking Union Medical College

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