Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure

Liu Zhihong; Cheng Xiansheng; Zhang Chaoyang; Zhao Yanfen; Zhang Yun; Ni Xinhai; Chen Baiping

doi:10.1007/BF02970581

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Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure

OriginalPaper | Updated：2021-08-27

- Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure
- Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure
- 中国结合医学杂志（英文版） 2000年6卷第2期页码：119-121
- Affiliations：
  
  Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences,Beijing
- Author bio：
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- DOI：10.1007/BF02970581
  中图分类号：
- 纸质出版日期：2000，
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Liu, Z., Cheng, X., Zhang, C. et al. Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure., CJIM 6, 119–121 (2000). https://doi.org/10.1007/BF02970581

Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al. Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure[J]. Chinese Journal of Integrative Medicine, 2000,6(2):119-121.
Liu, Z., Cheng, X., Zhang, C. et al. Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure., CJIM 6, 119–121 (2000). https://doi.org/10.1007/BF02970581 DOI：

Liu Zhihong, Cheng Xiansheng, Zhang Chaoyang, et al. Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure[J]. Chinese Journal of Integrative Medicine, 2000,6(2):119-121. DOI： 10.1007/BF02970581.

摘要

Objective: To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure.Methods: Effect of 16 cases treated with either SMI or potassium magnesium aspartate was observed by randomized crossover method and compared.Results: By using SMI for 2 weeks

the patients’ left ventricular ejective fraction (LVEF) was increased from 29.5 ± 9.0 to 36.6 ± 10.2 (P < 0.05)

the heart function of 68.75% patients was improved

no side effect or toxicity was observed. Potassium magnesium aspartate improved the heart function in 37. 50% patients only but showed no effect on LVEF.Conclusion: SMI is an effective and safe drug in treating patients with congestive heart failure.

Abstract

the patients’ left ventricular ejective fraction (LVEF) was increased from 29.5 ± 9.0 to 36.6 ± 10.2 (P < 0.05)

the heart function of 68.75% patients was improved

关键词

congestive heart failureShenmai injectionheart function

Keywords

congestive heart failureShenmai injectionheart function

references

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Xu Yali, Dong Jianying, LI Ziyu. Experimental study on cardiotonic effect of Shenmai Injection. Jianxi Medical J 1993;28(6): 323–326.

Liu Guiming, Wang Shuyun. Shenmai Injection in treating 36 cases of chronic congestive heart failure. Hunan J of TCM 1994;10(5):37–38.

Benack RT. Etiology of congestive heart failure in clinical medicine. Ann of the New York Acad. of Sciences 1969; 156:594–596.

Qin Lamei, Yang Jinduo, Liao Jiazhen. Further observation on effect of Shenmaisan on ATPase activity in my-ocardial cells of rats. Chinese J of Critical Care Medicine 1983;9(2):326–328.

Dong Quanzhen, Chen Keji. Commentary on studies of treating acute myocardial infarction with Shenmaisan. Chinese J of Integrated Traditional Chinese and Western Medicine 1983;3(1): 52.

Jin Xianqiao, Duan Shengfu, Niu Ruji, et al. Effect of Shenmai Injection and its ingredients on blood gas and hemorheology in rats with chronic anoxia. Chinese J of Integrated Traditional Chinese and Western Medicine 1995; 15(3):162–164.

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