Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients

Zhu Pi-jiang; Wei Xian-Jin; Zhao Wei-bing; Zhao Hua; Tian Jun-min; Qiu Jian-jun

doi:10.1007/BF03178483

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Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients

OriginalPaper | Updated：2021-08-27

- Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients
- Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients
- 中国结合医学杂志（英文版） 2001年7卷第3期页码：175-179
- Affiliations：
  
  Jiangsu Provincial TCM-WM Center of Nephropathy,Zhenjiang
- Author bio：
- Funds：
- DOI：10.1007/BF03178483
  中图分类号：
- 纸质出版日期：2001，
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Zhu, Pj., Wei, XJ., Zhao, Wb. et al. Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients., CJIM 7, 175 (2001). https://doi.org/10.1007/BF03178483

Zhu Pi-jiang, Wei Xian-Jin, Zhao Wei-bing, et al. Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients[J]. Chinese Journal of Integrative Medicine, 2001,7(3):175-179.
Zhu, Pj., Wei, XJ., Zhao, Wb. et al. Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients., CJIM 7, 175 (2001). https://doi.org/10.1007/BF03178483 DOI：

Zhu Pi-jiang, Wei Xian-Jin, Zhao Wei-bing, et al. Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients[J]. Chinese Journal of Integrative Medicine, 2001,7(3):175-179. DOI： 10.1007/BF03178483.

摘要

Objective: To explore the protective effect of Baoyuan Qiangshen Capsule No. II (BYQS) and its mechanism in treating chronic renal failure (CRF).Methods: Sixty CRF patients were divided into 2 groups randomly

the treated group used BYQS combined with Lotensin and the control group administered with essential amino acid combined with Lotensin. Changes of renal functions and tubular labelled proteins were observed.Results: The markedly effective rate and total effective rate of the treated group were 63.3% and 93.3% respectively

and those of the control group were 30.0% and 56.7% respectively

the effect of the treated group was obviously better than that of the control group (P < 0.01). In the treated group after medication

blood urea nitrogen

serum creatinine and clearance rate of creatinine were improved significantly (P < 0.01)

while Tamm-Horfau protein increased significantly (P < 0.01).Conclusion: BYQS could alleviate tubular interstitial injury significantly so as to improve the renal function and enhance the effective rate in treating CRF.

Abstract

and those of the control group were 30.0% and 56.7% respectively

the effect of the treated group was obviously better than that of the control group (P < 0.01). In the treated group after medication

blood urea nitrogen

serum creatinine and clearance rate of creatinine were improved significantly (P < 0.01)

关键词

Baoyuan Qiangshen Capsule No. IIchronic renal failureurine retinol binding proteinβ2-microglobulinN-acetyl-β-D-glucosamindaseTamm-Horfau protein

Keywords

Baoyuan Qiangshen Capsule No. IIchronic renal failureurine retinol binding proteinβ2-microglobulinN-acetyl-β-D-glucosamindaseTamm-Horfau protein

references

LU JR, TIAN J. Effect of renal tubular interstitial injury on renal function. Foreign Medicine Medical Fasciculus 1997;24(2):70–72.

ZHANG YK, WANG HY. Renal tubular interstitial lesion and progressive glomerular injury. J Chin Nephr 1994;10(1):39–42.

WANG HY, ZHENG FL, LIU YC, et al. Minutes of typing of primary renal glomerulopathy with treatment and diagnosis standard symposium. J Chin Medicine 1993;32(2):131–134.

YE YW, WANG YS, chief ed. National clinical operating rules and regulations. 2nd ed. Nanjing: East-Southern University Press, 1997:157–158, 259–263.

YAO J. Renal tubular labelled protein and its clinical significance. J Chin Nephr 1997;13(2):241–243.

LIU Q, HOU JS, MA JM, et al. Experimental study on effect of Cordyceps on chronic renal failure progress. J Chin Nephr 1995;11(2):81–82.

ZHANG YP. Progress on rhubarb in treating chronic renal failure. Chin J Integr Med (Chin) 1996;16(9):638–640.

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