Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone

Yu  Tu-gen; Zheng Yi-zhi; Zhu Jin-tu; Guo Wen

doi:10.1007/s11655-006-0277-1

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Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone

OriginalPaper | Updated：2021-08-27

- Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone
- Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone
- 中国结合医学杂志（英文版） 2006年12卷第4期页码：277-280
- Affiliations：
  
  Department of Dermatology, Zhejiang Provincial Hospital of Traditional Chinese Medicine,Hangzhou,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-006-0277-1
  中图分类号：
- 纸质出版日期：2006，
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Yu, Tg., Zheng, Yz., Zhu, Jt. et al. Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone., Chin. J Integ. Med. 12, 277–280 (2006). https://doi.org/10.1007/s11655-006-0277-1

Yu Tu-gen, Zheng Yi-zhi, Zhu Jin-tu, et al. Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone[J]. Chinese Journal of Integrative Medicine, 2006,12(4):277-280.
Yu, Tg., Zheng, Yz., Zhu, Jt. et al. Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone., Chin. J Integ. Med. 12, 277–280 (2006). https://doi.org/10.1007/s11655-006-0277-1 DOI：

Yu Tu-gen, Zheng Yi-zhi, Zhu Jin-tu, et al. Effect of treatment of rosacea in females by Chibixiao Recipe (赤鼻消方) in combination with minocycline and spironolactone[J]. Chinese Journal of Integrative Medicine, 2006,12(4):277-280. DOI： 10.1007/s11655-006-0277-1.

摘要

To observe the clinical efficacy of Chibixiao Recipe (赤鼻消方

CBX) in combination with minocycline and spironolactone in treating rosacea in females. Sixty-eight women with rosacea were randomly assigned to the treated group (48 cases) and the control group (20 cases)

both of which were treated with minocycline and spironolactone taken orally

but to the treated group

the Chinese herbal recipe

CBX was given additionally. Besides

cryotherapy with liquid nitrogen was applied to those with apparent capillary dilatation. The therapeutic course for both groups was 8 weeks. The levels of serum testosterone before and after treatment were determined by radioimmunoassay (RIA)

and a 4-month follow-up was conducted. In the treated group the cure-markedly effective rate was 87.5% and the recurrent rate was 6.5%

while in the control group

they were 45.0% and 41.2% respectively. Comparisons in the indexes between the two groups all showed significant difference (both P<0.01)

with the cure-markedly effective rate higher

and the recurrent rate lower in the treated group. The serum level of testosterone got lowered in both groups (P<0.05 and P<0.01)

but the lowering in the treated group was more significant

showing significance when compared with that in the control group (P<0.01). CBX in combination with Western medicine has effect in treating rosacea superior to that of Western medicine alone

and could effectively reduce recurrent rate and the serum level of testosterone.

Abstract

To observe the clinical efficacy of Chibixiao Recipe (赤鼻消方

both of which were treated with minocycline and spironolactone taken orally

but to the treated group

the Chinese herbal recipe

CBX was given additionally. Besides

and a 4-month follow-up was conducted. In the treated group the cure-markedly effective rate was 87.5% and the recurrent rate was 6.5%

while in the control group

they were 45.0% and 41.2% respectively. Comparisons in the indexes between the two groups all showed significant difference (both P<0.01)

with the cure-markedly effective rate higher

and the recurrent rate lower in the treated group. The serum level of testosterone got lowered in both groups (P<0.05 and P<0.01)

but the lowering in the treated group was more significant

showing significance when compared with that in the control group (P<0.01). CBX in combination with Western medicine has effect in treating rosacea superior to that of Western medicine alone

and could effectively reduce recurrent rate and the serum level of testosterone.

关键词

female rosaceaTestosteroneChibixiao RecipeMinocyclinespironolactone

Keywords

female rosaceaTestosteroneChibixiao RecipeMinocyclinespironolactone

references

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