Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease
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Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease
Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease
中国结合医学杂志(英文版)2007年13卷第2期 页码:125-127
Affiliations:
Zhujiang Hospital, Nanfang Medical University,Guangzhou,China
Author bio:
Funds:
Supported by Guangdong Provincial Natural Science Foundation (No. 06024432) and Scientific Project of Administration of Traditional Chinese Medicine of Guangdong Province (No. 2060128)
Liang, Dh., Chen, Yq., Li, Zl. et al. Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease., Chin. J Integ. Med. 13, 125–127 (2007). https://doi.org/10.1007/s11655-007-0125-6
Liang Dong-hui, Chen Yun-qin, Li Zhi-liang, et al. Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease[J]. Chinese Journal of Integrative Medicine, 2007,13(2):125-127.
Liang, Dh., Chen, Yq., Li, Zl. et al. Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease., Chin. J Integ. Med. 13, 125–127 (2007). https://doi.org/10.1007/s11655-007-0125-6DOI:
Liang Dong-hui, Chen Yun-qin, Li Zhi-liang, et al. Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease[J]. Chinese Journal of Integrative Medicine, 2007,13(2):125-127. DOI: 10.1007/s11655-007-0125-6.
Study on the relationship between serum high density lipoprotein and Pi-deficiency syndrome in patients with coronary heart disease
摘要
To explore the relationship of Pi (脾)-deficiency syndrome in TCM with the change of serum high density lipoprotein (HDL) in blood lipid metabolic disorder. Sixty-eight patients with confirmed coronary heart disease (CHD) were selected for TCM syndrome typing into Pideficiency (PD) group and non-Pi-deficiency (NPD) group. Routine blood lipids and serum lipoprotein electrophoretogram (SLPG) were determined in all patients to analyze the total content of HDL and its relative contents of sub-components HDL1–5
as well as their relation with PD syndrome. Besides
a healthy control group (62 cases) was set up. The level of serum HDL-C was lowered
SLPG abnormality rate increased in the patients with CHD
with total HDL and the relative contents of subcomponent HDL1 and HDL3 significantly lower than those in the healthy control group (P<0.01). The total HDL
HDL1 and HDL3 in the PD group were also lower than those in the NPD group (P<0.05
P<0.01). Serum HDL and its sub-components showed a definite relation with TCM PD syndrome type
therefore
further exploring the granular specificity of HDL and its sub-components as well as their influence on reverse cholesterol transport (RCT) may hopefully provide clues for developing RCT regulatory Chinese new drugs and for CHD prevention and treatment.
Abstract
To explore the relationship of Pi (脾)-deficiency syndrome in TCM with the change of serum high density lipoprotein (HDL) in blood lipid metabolic disorder. Sixty-eight patients with confirmed coronary heart disease (CHD) were selected for TCM syndrome typing into Pideficiency (PD) group and non-Pi-deficiency (NPD) group. Routine blood lipids and serum lipoprotein electrophoretogram (SLPG) were determined in all patients to analyze the total content of HDL and its relative contents of sub-components HDL1–5
as well as their relation with PD syndrome. Besides
a healthy control group (62 cases) was set up. The level of serum HDL-C was lowered
SLPG abnormality rate increased in the patients with CHD
with total HDL and the relative contents of subcomponent HDL1 and HDL3 significantly lower than those in the healthy control group (P<0.01). The total HDL
HDL1 and HDL3 in the PD group were also lower than those in the NPD group (P<0.05
P<0.01). Serum HDL and its sub-components showed a definite relation with TCM PD syndrome type
therefore
further exploring the granular specificity of HDL and its sub-components as well as their influence on reverse cholesterol transport (RCT) may hopefully provide clues for developing RCT regulatory Chinese new drugs and for CHD prevention and treatment.
关键词
high density lipoproteincoronary heart diseasePi-deficiency syndrome
Keywords
high density lipoproteincoronary heart diseasePi-deficiency syndrome
references
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Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences
Academy of Chinese Medical Sciences
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