Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure

Xi-li Wu; Wan-sen Sun; Wang-gang Zhang; Cheng-lin Qiao; Run-xia Liu

doi:10.1007/s11655-008-0098-0

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Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure

OriginalPaper | Updated：2021-08-27

- Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure
- Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure
- 中国结合医学杂志（英文版） 2008年14卷第2期页码：98-102
- Affiliations：
  
  1. Department of the Integrated Chinese and Western Medicine, Shaanxi Province Traditional Chinese Medical Key Department of Nephrology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University,Xi’an,China
  2. Department of Hematology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University,Xi’an,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-008-0098-0
  中图分类号：
- 纸质出版日期：2008，
  
  网络出版日期：2008-8-6，
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Wu, Xl., Sun, Ws., Zhang, Wg. et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure., Chin. J. Integr. Med. 14, 98–102 (2008). https://doi.org/10.1007/s11655-008-0098-0

Xi-li Wu, Wan-sen Sun, Wang-gang Zhang, et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure[J]. Chinese Journal of Integrative Medicine, 2008,14(2):98-102.
Wu, Xl., Sun, Ws., Zhang, Wg. et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure., Chin. J. Integr. Med. 14, 98–102 (2008). https://doi.org/10.1007/s11655-008-0098-0 DOI：

Xi-li Wu, Wan-sen Sun, Wang-gang Zhang, et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure[J]. Chinese Journal of Integrative Medicine, 2008,14(2):98-102. DOI： 10.1007/s11655-008-0098-0.

摘要

To investigate the mechanism of Trilogy Detoxicating Therapy in treating patients with chronic renal failure (CRF). A total of 142 patients were assigned to the Trilogy Detoxicating Therapy group (the treatment group

82 patients) and the Western medicine treatment group (the control group

60 patients). All of the patients were treated with NovoNorm 1 mg and metformin hydrochloride tablets 0.15 g thrice per day for lowering the blood glucose

as well as Perindopril 4 mg twice daily for lowering blood pressure

recombinant human erythropoietin 2 000 U and a hypodermic injection thrice a week for rectifying anemia

30 days as one course of treatment

and all patients were treated for two courses. Patients in the treatment group were treated with the Trilogy Detoxicating Therapy [dispersing the five-zang (脏) organs

expelling toxins through colonic dialysis and skin dialysis fumigation] in addition to the aforementioned drugs. Parameters observed and recorded in the study included renal function [serum creatinine (SCr)

blood urea nitrogen (BUN)]

blood lipids [triglyceride (TG)

total cholesterol (TC)

low-density lipoprotein C (LDL-C)

high-density lipoprotein C (HDL-C)]

plasma total protein (TP)

hemoglobin (Hb)

serum interleukin-6 (IL-6)

and tumor necrosis factor-α (TNF-α) before and after the treatment. After two courses of treatment

the levels of SCr

BUN

LDL-C

serum IL-6 and TNF-α decreased significantly

meanwhile HDL-C increased in the treatment group (P<0.05 or P<0.01). In contrast

no obvious changes of the above mentioned items occurred in the control group. In both groups

the levels of TP and Hb were significantly elevated (P<0.05 or P<0.01)

but the changes were more obvious in the treatment group (P<0.01). Trilogy Detoxicating Therapy played a therapeutic role on patients with CRF possibly through lowering the levels of blood lipids

serum IL-6 and TNF-α.

Abstract

82 patients) and the Western medicine treatment group (the control group

60 patients). All of the patients were treated with NovoNorm 1 mg and metformin hydrochloride tablets 0.15 g thrice per day for lowering the blood glucose

as well as Perindopril 4 mg twice daily for lowering blood pressure

recombinant human erythropoietin 2 000 U and a hypodermic injection thrice a week for rectifying anemia

30 days as one course of treatment

and all patients were treated for two courses. Patients in the treatment group were treated with the Trilogy Detoxicating Therapy [dispersing the five-zang (脏) organs

blood urea nitrogen (BUN)]

blood lipids [triglyceride (TG)

total cholesterol (TC)

low-density lipoprotein C (LDL-C)

high-density lipoprotein C (HDL-C)]

plasma total protein (TP)

hemoglobin (Hb)

serum interleukin-6 (IL-6)

and tumor necrosis factor-α (TNF-α) before and after the treatment. After two courses of treatment

the levels of SCr

BUN

LDL-C

serum IL-6 and TNF-α decreased significantly

meanwhile HDL-C increased in the treatment group (P<0.05 or P<0.01). In contrast

no obvious changes of the above mentioned items occurred in the control group. In both groups

the levels of TP and Hb were significantly elevated (P<0.05 or P<0.01)

but the changes were more obvious in the treatment group (P<0.01). Trilogy Detoxicating Therapy played a therapeutic role on patients with CRF possibly through lowering the levels of blood lipids

serum IL-6 and TNF-α.

关键词

Trilogy Detoxicating Therapychronic renal failureinterleukin-6tumor necrosis factor-α

Keywords

Trilogy Detoxicating Therapychronic renal failureinterleukin-6tumor necrosis factor-α

references

Yu YM, Cui JQ, Zhang F, et al. Chinese drugs for invigorating spleen to remove dampness, activating blood circulation to eliminate turbid in retarding progression of chronic renal failure. Chin J Integr Tradit West Med (Chin) 2000;20(10):727–728.

Wu XX, Zhang X. Clinical study on treating chronic renal failure by combined use of TCM and WM therapy. J Emerg Tradit Chin Med (Chin) 2001;10(4):198–199.

Deng YH, Yin GY. Research progression of integrated traditional Chinese and Western medicine on chronic renal function failure. Modern J Integr Tradit Chin West Med (Chin) 2004;13(8):1109–1110.

Wang HY, ed. Nephrology. 2nd ed. Beijing: People’s Medical Publishing House, 1998:1385.

Xu RJ, Wang GH, Zhao JW, et al. Determination and signficance of plasma IL-1β, IL-6, TNF-α undergoing hemodialysis in chronic renal failure patients. J Radioimmunol (Chin) 1998;11(4):193–195.

Li H, Li X, Duan L, et al. Inhibition of lovastatin on proliferation and expression of proinflammatory cytokines in cultured human glomerular mesangial cells. Chin Med J 2003; 116(9):1366–1369.

Xie JP, Feng JC, Zhang GY, et al. Study on the changes of serum IL-2, IL-6 and TNF-α levels in patients with chronic glomerulonephritis. J Radioimmunol 2003;16(6):348–350.

Hao L, Yang MG. Dependability study of plasma and uria IL-6 with immunitic renal disease of clinical pathology. Acta Univ Med Nahui (Chin) 2001;36(6):440–442.

Qi H, Dai Y, Wang SY, et al. The change and significance of plasma tumor necrosis factors-α and soluble tumor necrosis fators-α receptors in patients with chronic renal insufficiency. Guangdong Med J (Chin) 1999;20(4):262–263.

Shen AB, Yang L, Zhao JT, et al. The detection and clinical significance of platelet-activated factor (PAF) and tumor necrosis factor-α (TNF-α) in patients with uremia of chronic glomerulonephritis. Hebei Med J (Chin) 2000;2(4):252–253.

Wang SF, Guan SP, Li JJ, et al. The changes of lipid metabolism in chronic renal insufficiency. Chin Crit Care Med (Chin) 1996;8:158–159.

Guijarro C, Keane WF. Lipid-induced glomerular injury (editorial). Nephron 1994;67:1–3.

Yang X, Wei Y, Yie RG, et al. The effect of Enapril on glomerular extracellular matrix accumulation in rats with 5/6 renal mass ablation. Chin Crit Care Med (Chin) 2000;12 (4):198–201.

Sun WS, Wu XL, Qiao CL, et al. Chronic renal failure treated by Double Toxin-dissipating therapy. Shaanxi J Tradit Chin Med (Chin) 2004;28(12):1068–1077.

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