从COVID-19的分子病理学到黑种草作为一种治疗选择:以科学为基础的证据，神话还是现实？

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从COVID-19的分子病理学到黑种草作为一种治疗选择:以科学为基础的证据，神话还是现实？

Review | Updated：2022-03-18

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- 从COVID-19的分子病理学到黑种草作为一种治疗选择:以科学为基础的证据，神话还是现实？
- From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality
- Chinese Journal of Integrative Medicine 2022年28卷第1期页码：88-95
- Affiliations：
  
  1.Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka (75471), Saudi Arabia
  2.Department of Microbiology, Government College University, Faisalabad (38000), Pakistan
  3.Department of Microbiology, University of Health Sciences, Lahore (54600),Pakistan
  4.Department of Allied Health Sciences, Sargodha Medical College, University of Sargodha, Sargodha (40100),Pakistan
  5.University of Health Sciences, Lahore (54600),Pakistan
  6.University Institute of Diet and Nutritional Sciences,Faculty of Allied Health Sciences, The University of Lahore,Lahore (54590), Pakistan
- Author bio：
  
  Dr. Muhammad Imran, E-mail: mi.bannu@yahoo.com
  Dr. Muhammad Imran, E-mail: mi.bannu@yahoo.com
- Funds：
- DOI：10.1007/s11655-021-3311-z
  中图分类号：
- 纸质出版日期：2022-01-01，
  
  网络出版日期：2021-09-29，
  
  录用日期：2021-03-10
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Muhammad Atif, Farrah Naz, Junaid Akhtar, 等. 从COVID-19的分子病理学到黑种草作为一种治疗选择:以科学为基础的证据，神话还是现实？[J]. Chinese Journal of Integrative Medicine, 2022,28(1):88-95.

Muhammad Atif, Farrah Naz, Junaid Akhtar, et al. From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality[J]. Chinese Journal of Integrative Medicine, 2022,28(1):88-95.
Muhammad Atif, Farrah Naz, Junaid Akhtar, 等. 从COVID-19的分子病理学到黑种草作为一种治疗选择:以科学为基础的证据，神话还是现实？[J]. Chinese Journal of Integrative Medicine, 2022,28(1):88-95. DOI： 10.1007/s11655-021-3311-z.

Muhammad Atif, Farrah Naz, Junaid Akhtar, et al. From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality[J]. Chinese Journal of Integrative Medicine, 2022,28(1):88-95. DOI： 10.1007/s11655-021-3311-z.

摘要

COVID-19病毒是一种专门针对人类的病毒病原体

特异性地侵犯人的呼吸系统

引起病毒性肺炎. 这种不寻常的病毒性肺炎正在迅速蔓延到世界各地

目前影响到约1.05亿人

导致230万人死亡. 本文描述了COVID-19的历史、基因组特征、复制和发病机制

并特别强调黑种草作为一种治疗选择. 黑种草的种子在几个世纪以来被广泛应用于疾病的预防及治疗. 这篇综述总结其潜在作用

并从生物信息学、细胞系和动物模型水平探讨黑种草种子抗COVID-19感染的作用机制.

Abstract

COVID-19 virus is a causative agent of viral pandemic in human beings which specifically targets respiratory system of humans and causes viral pneumonia. This unusual viral pneumonia is rapidly spreading to all parts of the world

currently affecting about 105 million people with 2.3 million deaths. Current review described history

genomic characteristics

replication

and pathogenesis of COVID-19 with special emphasis on

Nigella sativum

(

N. sativum

) as a treatment option.

N. sativum

seeds are historically and religiously used over the centuries

both for prevention and treatment of different diseases. This review summarizes the potential role of

N. sativum

seeds against COVID-19 infection at levels of

in silico

cell lines and animal models.

关键词

Keywords

coronavirusnCoV-19COVID-19Nigella sativumreview

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Hong Kong Modern Chinese Medicine Research & Development Center

Department of Cardiology,Dongzhimen Hospital, Beijing University of Chinese Medicine

Cardiovascular Disease Center, Xiyuan Hospital, National Clinical Research Center for Chinese Medicine Cardiology,China Academy of Chinese Medical Sciences

Good Clinical Practice Development, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University

Department of Pharmacy, Sun Yat-sen Memorial Hospital, Sun Yat-sen University

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